Evidence map›Paper›PMID 22884803›Full record

ReviewLife sciences2013

Modulation of the cannabinoid receptors by hemopressin peptides.

Martha G Bomar, Amit K Galande

Abstract readReview
In one paragraph

Review in Life sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

  1. Cannabis and Cannabinoids in Reproduction and Fertility: Where We Stand.Reproductive sciences (Thousand Oaks, Calif.) · 2022
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. The Endocannabinoid Signaling System in the CNS: A Primer.International review of neurobiology · 2015
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Martha G BomarCenter for Advanced Drug Research (CADRE), SRI International, United States.
Amit K Galande
SRI International · US

Funding

Aggregation Properties of HemopressinR21DA034422 · NIDA · SRI INTERNATIONAL · PI NAYAK, SURENDRA KUMAR · 2012 to 2013
$498k
NIDA NIH HHS R21 DA034422
6 · The paper itself

Abstract

Changes in the endocannabinoid system are implicated in numerous diseases, making it an attractive target for pharmaceutical development. The endocannabinoid receptors have traditionally been thought to act through the effects of lipophilic messengers called cannabinoids. The exciting finding of endocannabinoid system modulation by the nonapeptide hemopressin and its N-terminal extensions has highlighted the complexity of cannabinoid biology and pharmacology and sparked interest for therapeutic purposes. However, many questions surrounding the generation and regulation of the hemopressin peptides, the self-assembly of hemopressin and the potential for drug development based on hemopressin remain and are discussed in this review.

Indexed as

Cannabinoid Receptor ModulatorsAnimalsEndocannabinoidsHemoglobinsHumansLigandsPeptide FragmentsPeptidesReceptors, CannabinoidCannabinoid Receptor ModulatorsEndocannabinoidsHemoglobinshemopressinLigandsPeptide FragmentsPeptidesReceptors, Cannabinoid

Identifiers

PMID22884803
PMCPMC3594051
OpenAlexW2049810522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.