ArticleBMC public health2012
Arsenic exposure through drinking water increases the risk of liver and cardiovascular diseases in the population of West Bengal, India.
Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.
- Association between arsenic exposure and inflammatory cytokines and C-reaction protein: A systematic review and meta-analysis.Medicine · 2022Pooled it
- Review
- Perspective on health and ecological risk assessments of potentially toxic metal(loid)s using aquatic biodiversity as biomonitoring indicators.Toxicology reports · 2025Review
- Ferroptosis in Toxicology: Present and Future.International journal of molecular sciences · 2025Review
- Disentangling the role of selenium in antagonizing the toxicity of arsenic and cadmium.Archives of toxicology · 2025Review
- Arsenic health risks and interaction with salinity in coastal areas of Bangladesh.Frontiers in public health · 2025Article
- Copper, Iron, Cadmium, and Arsenic, All Generated in the Universe: Elucidating Their Environmental Impact Risk on Human Health Including Clinical Liver Injury.International journal of molecular sciences · 2024Review
- Arsenic exposure and increasedRedox biochemistry and chemistry · 2023Article
- Long-term effects of prenatal arsenic exposure from gestational day 9 to birth on lung, heart, and immune outcomes in the C57BL/6 mouse model.Toxicology letters · 2023Article
- Route of Arsenic Exposure Differentially Impacts the Expression of Genes Involved in Gut-Mucosa-Associated Immune Responses and Gastrointestinal Permeability.International journal of molecular sciences · 2023Article
- Article
- The Effect of Broccoli Extract in Arsenic-Induced Experimental Poisoning on the Hematological, Biochemical, and Electrophoretic Parameters of the Liver and Kidney of Rats.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Mitochondrial Dysfunction in Arsenic-Induced Hepatotoxicity: Pathogenic and Therapeutic Implications.Biological trace element research · 2022Review
- Occupational exposure of rural workers to pesticides in a vegetable-producing region in Brazil.Environmental science and pollution research international · 2021Article
- Pentoxifylline Attenuates Arsenic Trioxide-Induced Cardiac Oxidative Damage in Mice.Oxidative medicine and cellular longevity · 2021Article
- Biochemical and histological effects of five weeks ingestion of Zamzam water on the liver and kidneys of Wistar rats.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Protective effect ofVeterinary world · 2020Article
- Urinary Metals Concentrations and Biomarkers of Autoimmunity among Navajo and Nicaraguan Men.International journal of environmental research and public health · 2020Article
- An assessment of arsenic hazard in groundwater-soil-rice system in two villages of Nadia district, West Bengal, India.Environmental geochemistry and health · 2019Article
- Application of water quality index, synthetic pollution index, and geospatial tools for the assessment of drinking water quality in the Indus Delta, Pakistan.Environmental monitoring and assessment · 2019Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundArsenic is a natural drinking water contaminant affecting 26 million people in West Bengal, India. Chronic arsenic exposure causes cancer, cardiovascular disease, liver disease, neuropathies and ocular diseases. The aims of the present study were to assess bioindicators of hepatocellular injury as indicated by the levels of liver enzymes, to determine the auto immune status, as indicated by the amounts of anti-nuclear antibodies (ANA) and anti-dsDNA antibodies in their serum, and to predict cardiovascular risk in the arsenic exposed population.
methodsEffect of chronic arsenic exposure on liver was determined by liver function tests. Autoimmune status was measured by measuring ANA and anti-dsDNA in serum. Inflammatory cytokines associated with increased cardiovascular disease risk, IL6, IL8 and MCP-1 were determined.
resultsOur results indicated that serum levels of bilirubin, alanine transaminase, aspartate transaminase, alkaline phosphatase and ANA were increased in the arsenic exposed population. Serum levels of IL6 and IL8 also increased in the arsenic exposed group.
conclusionsChronic arsenic exposure causes liver injury, increases the serum levels of autoimmune markers and imparts increased cardiovascular risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.