Evidence map›Paper›PMID 22882399›Full record

Trial reportThe American journal on addictions

Postprison release HIV-risk behaviors in a randomized trial of methadone treatment for prisoners.

Monique E Wilson, Timothy W Kinlock, Michael S Gordon, Kevin E O'Grady, Robert P Schwartz

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00378079 (Methadone Maintenance for Prisoners), which is not on this map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00378079 phase3completednot on this map

Methadone Maintenance for Prisoners

TypeinterventionalSponsorFriends Research Institute, Inc.Ran2003 to 2008Enrolled211ConditionsHeroin AddictionArmsCounseling Only, Counseling + Transfer, Counseling + Methadone
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pharmacological interventions for drug-using offenders.The Cochrane database of systematic reviews · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Monique E WilsonFriends Research Institute, Inc., Baltimore, Maryland 21201, USA. mwilson@friendsresearch.org
Timothy W Kinlock
Michael S Gordon
Kevin E O'Grady
Robert P Schwartz
Friends Research Institute · USUniversity of Baltimore · USUniversity of Maryland, College Park · US

Funding

Methadone Maintenance for PrisonersR01DA016237 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI KINLOCK, TIMOTHY W · 2003 to 2007
$2.9M
NIDA NIH HHS R01 DA016237NIDA NIH HHS R01DA16237
6 · The paper itself

Abstract

backgroundThis secondary analysis examined the impact of methadone initiated in prison on postrelease HIV risk behaviors. The parent study was a three-group randomized clinical trial in which participants received drug abuse counseling in prison and were randomly assigned to: (1) passive referral to substance abuse treatment upon release; (2) guaranteed methadone treatment admission upon release; and (3) methadone in prison and guaranteed continuation of methadone upon release.

methodsParticipants were 211 adult males with preincarceration histories of opiate dependence. The AIDS Risk Assessment was administered at baseline (in prison) and at 1-, 3-, 6-, and 12-month postrelease. Data were analyzed for the entire sample (N = 211) as well as the subsamples who reported injecting drugs in the 30 days prior to incarceration (n = 131) and who reported having unprotected sex in that time frame (n = 144) using generalized linear mixed model on an intent-to-treat basis.

resultsThere were no significant changes in sex- or drug-risk by Condition over Time. There were significant Time and Condition main effects for the total sample as well as the injector subsample for drug-risk behaviors. There were no significant Condition main effects for HIV sex-risk behaviors, but there were significant Time main effects.

conclusionsMethadone initiated in prison or immediately postrelease is associated with reduced HIV drug-risk compared to counseling in prison without methadone and passive referral to treatment at release. Participation in several drug- and sex-risk behaviors also showed significant declines during the postrelease time periods.

Indexed as

HIV InfectionsOpiate Substitution TreatmentPrisonersRisk Reduction BehaviorAdultHumansLinear ModelsMaleMethadoneNarcoticsNeedle SharingOpioid-Related DisordersUnited StatesUnsafe SexMethadoneNarcotics

Identifiers

PMID22882399
PMCPMC3422766
OpenAlexW1941462008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.