Evidence map›Paper›PMID 22882000›Full record

ArticleJournal of the American Geriatrics Society2012

Prevalence of cognitive impairment in older adults with heart failure.

Tanya R Gure, Caroline S Blaum, Bruno Giordani, Todd M Koelling, Andrzej Galecki, Susan J Pressler, Scott L Hummel, Kenneth M Langa

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Left ventricular remodeling and diastolic dysfunction predict cognitive decline in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  8. Article
  9. Relationship between cardiac index and brain volume in the UK Biobank.Cerebral circulation - cognition and behavior · 2026
    Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Trajectory of Cognitive Function After Incident Heart Failure.medRxiv : the preprint server for health sciences · 2024
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tanya R GureDivision of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA. tanruff@umich.edu
Caroline S Blaum
Bruno Giordani
Todd M Koelling
Andrzej Galecki
Susan J Pressler
Scott L Hummel
Kenneth M Langa
University of Michigan–Ann Arbor · USMichigan Medicine · USVA Ann Arbor Healthcare System · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
MICHIGAN INSTITUTE FOR CLINICAL AND HEALTH RESEARCH (MICHR) (UL1): (BPCA)UL1RR024986 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2007 to 2011
$51.2M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Andrzej T Galecki · 2004 to 2026
$29.2M
The Cost of DementiaR01AG030155 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 2007 to 2011
$3.1M
Patterns and Predictors of Cognitive DeclineR01AG027010 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANGA, KENNETH M · 2006 to 2008
$1.2M
Diet and pathophysiology of heart failure with preserved ejection fractionK23HL109176 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUMMEL, SCOTT L · 2011 to 2015
$795k
NCRR NIH HHS UL1 RR024986NHLBI NIH HHS K23 HL109176NIA NIH HHS P30 AG024824NIA NIH HHS R01 AG027010NIA NIH HHS R01 AG027010-02S1NIA NIH HHS R01 AG030155NIA NIH HHS U01 AG009740NIA NIH HHS U01 AG09740
6 · The paper itself

Abstract

objectivesTo determine the prevalence of cognitive impairment in older adults with heart failure (HF).

designCross-sectional analysis of the 2004 wave of the nationally representative Health and Retirement Study linked to 2002 to 2004 Medicare administrative claims.

settingUnited States, community.

participantsSix thousand one hundred eighty-nine individuals aged 67 and older. MEASUREMENTS: An algorithm was developed using a combination of self- and proxy report of a heart problem and the presence of one or more Medicare claims in administrative files using standard HF diagnostic codes. On the basis of the algorithm, three categories were created to characterize the likelihood of a HF diagnosis: high or moderate probability of HF, low probability of HF, and no HF. Cognitive function was assessed using a screening measure of cognitive function or according to proxy rating. Age-adjusted prevalence estimates of cognitive impairment were calculated for the three groups.

resultsThe prevalence of cognitive impairment consistent with dementia in older adults with HF was 15%, and the prevalence of mild cognitive impairment was 24%. The odds of dementia in those with HF were significantly higher, even after adjustment for age, education level, net worth, and prior stroke (odds ratio = 1.52, 95% confidence interval = 1.14-2.02).

conclusionCognitive impairment is common in older adults with HF and is independently associated with risk of dementia. A cognitive assessment should be routinely incorporated into HF-focused models of care.

Indexed as

AgedAged, 80 and overAlgorithmsChi-Square DistributionCognition DisordersCross-Sectional StudiesDemographyFemaleHeart FailureHumansLogistic ModelsMaleMedicarePrevalenceUnited States

Identifiers

PMID22882000
PMCPMC3445700
OpenAlexW2044018155

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.