Evidence map›Paper›PMID 22880626›Full record

ArticleJournal of the American Geriatrics Society2012

Venous thromboembolism in nursing home residents: role of selected risk factors.

Cynthia L Leibson, Tanya M Petterson, Carin Y Smith, Kent R Bailey, Aneel A Ashrani, John A Heit

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cynthia L LeibsonDivisions of Epidemiology, Department of Health Sciences Research, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA. leibson@mayo.edu
Tanya M Petterson
Carin Y Smith
Kent R Bailey
Aneel A Ashrani
John A Heit
Mayo Clinic in Florida · USMayo Clinic · US

Funding

RISK FACTORS FOR VENOUS THROMBOEMBOLISM IN THE COMMUNITYR01HL066216 · NHLBI · MAYO CLINIC ROCHESTER · PI ASHRANI, ANEEL ARJUN, BAILEY, KENT R · 2001 to 2019
$10.4M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
ROCHESTER EPIDEMIOLOGY PROJECTR01AR030582 · NIAMS · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A · 1986 to 2009
$5.1M
The burden of venous thromboembolism within the nursing home populationR01AG031027 · NIA · MAYO CLINIC ROCHESTER · PI LEIBSON, CYNTHIA L · 2007 to 2010
$1.5M
NHLBI NIH HHS R01 HL066216NHLBI NIH HHS R01HL 66216-9NIAMS NIH HHS R01 AR030582NIA NIH HHS R01 AG031027NIA NIH HHS R01 AG 034676NIA NIH HHS R01 AG034676NIA NIH HHS R01AG 31027-4
6 · The paper itself

Abstract

objectivesTo provide nursing home (NH)-specific estimates to assess whether venous thromboembolism (VTE) risk factors identified for the general population apply to NH residents.

designPopulation-based case-control study.

settingOlmsted County, Minnesota.

participantsAll county residents with symptomatic objectively diagnosed incident VTE while resident in a NH from 1988 through 2000 (N = 182) and two age-, sex-, calendar-year-matched non-VTE Olmsted County NH residents per case (N = 364). MEASUREMENTS: Provider-linked medical records were reviewed to obtain information on active malignancy and recent hospitalization, surgery, trauma, or fracture as of index date (case's VTE date; respective provider registration date for controls). Risk factor prevalence and VTE-associated odds ratios (OR) were estimated and compared with previously obtained data for all Olmsted County residents from 1988 through 2000. For analyses, both groups were limited to individuals aged 65 and older.

resultsIn NH residents, active malignancy, recent hospitalization, and recent surgery significantly increased VTE risk, but the magnitude of risk appeared much lower than general population estimates (e.g., for major surgery, OR = 2.5, 95% confidence interval (CI) = 1.4-4.3 for NH residents vs OR = 11, 95% CI = 7.0-17 for general population). In general, the prevalence of all evaluated VTE risk factors appeared much higher in NH controls than in general population controls. Thromboprophylaxis rates appeared higher for NH cases and controls than in the general population; disconcertingly, 47% of NH cases received prophylaxis.

conclusionAlthough general population VTE risk factors (active cancer and recent hospitalization or surgery) can identify NH residents at higher risk for VTE, these exposures do not adequately stratify VTE risk for thromboprophylaxis recommendations. Further research into NH-specific risk factors and prophylaxis effectiveness is required.

Indexed as

Nursing HomesAgedAged, 80 and overCase-Control StudiesFemaleHumansLogistic ModelsMaleMinnesotaPrevalenceRetrospective StudiesRisk FactorsVenous Thromboembolism

Identifiers

PMID22880626
PMCPMC3445699
OpenAlexW1976003761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.