Evidence map›Paper›PMID 22879850›Full record

ArticleMaedica2011

Manifestations of systemic lupus erythematosus.

Manole Cojocaru, Inimioara Mihaela Cojocaru, Isabela Silosi, Camelia Doina Vrabie

Registry-linked trialAbstract read
In one paragraph

Article in Maedica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063668 (Serum Autotaxin as a Potential Biomarker in Systemic Lupus Erythematosus Patients and Its Relation to Disease Activity.), which is not on this map. Cited by 155 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06063668 unknown statusnot on this mapstarted 2023, after this paper: background citation

Serum Autotaxin as a Potential Biomarker in Systemic Lupus Erythematosus Patients and Its Relation to Disease Activity.

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled94ConditionsSLE (Systemic Lupus)
3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  17. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manole Cojocaru"Titu Maiorescu" University, Faculty of Medicine, Department of Physiology, Center for Rheumatic Diseases, Bucharest.
Inimioara Mihaela Cojocaru
Isabela Silosi
Camelia Doina Vrabie

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a chronic, multifaceted autoimmune inflammatory disease that can affect any part of the body. SLE is a disease of unknown aetiology with a variety of presenting features and manifestations. Interest in the disease has been stimulated in recent years, and improved methods of diagnosis have resulted in a significant increase in the number of cases recognized. It is apparent that it can no longer be regarded as a rare disease. The majority of the pathology in SLE is related to deposits of immune complexes in various organs, which triggers complement and other mediators of inflammation. Symptoms vary from person to person, and may come and go, depend on what part of the body is affected, can be mild, moderate, or severe. Diagnosis can be difficult because lupus mimics many other diseases; it requires clinical and serologic criteria.

Indexed as

clinical manifestationslaboratory abnormalitiessystemic lupus erythematosus

Identifiers

PMID22879850
PMCPMC3391953

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.