Evidence map›Paper›PMID 22878103›Full record

ReviewInternational review of cell and molecular biology2012

Cytoskeleton assembly in Toxoplasma gondii cell division.

Brooke Anderson-White, Josh R Beck, Chun-Ti Chen, Markus Meissner, Peter J Bradley, Marc-Jan Gubbels

Open access · greenAbstract readReview
In one paragraph

Review in International review of cell and molecular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 123 citations in OpenAlex.

  1. Article
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  4. The Centrocone Protein SMC_N1 Is Important for the Proliferation ofAnimals : an open access journal from MDPI · 2026
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  6. bioRxiv : the preprint server for biology · 2025
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  12. Architecture of theProceedings of the National Academy of Sciences of the United States of America · 2024
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  16. Co-dependent formation of thebioRxiv : the preprint server for biology · 2024
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  17. Article
  18. Article
  19. Atlas ofeLife · 2023
    Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Brooke Anderson-WhiteDepartment of Biology, Boston College, Chestnut Hill, Massachusetts, USA.
Josh R Beck
Chun-Ti Chen
Markus Meissner
Peter J Bradley
Marc-Jan Gubbels
Boston College · USUniversity of California, Los Angeles · USUniversity of Glasgow · GB

Funding

Treatments for Nipah Virus InfectionU54AI057159 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WHELAN, SEAN PJ · 2003 to 2013
$113.7M
MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIST32AI007323 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peter John Bradley · 1988 to 2026
$8.6M
The Role of Toxoplasma Rhoptries in Host Cell InfectionR01AI064616 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BRADLEY, PETER JOHN · 2006 to 2016
$3.5M
Cytoskeleton scaffold assembly in Toxoplasma gondiiR01AI081924 · NIAID · BOSTON COLLEGE · PI GUBBELS, MARC-JAN · 2009 to 2012
$1.4M
NIAID NIH HHS R01 AI064616NIAID NIH HHS R01AI064616NIAID NIH HHS R01 AI081924NIAID NIH HHS R01AI081924NIAID NIH HHS T32 AI007323NIAID NIH HHS T32-AI07323NIAID NIH HHS U54 AI057159NIAID NIH HHS U54AI057159Wellcome Trust 087582Wellcome Trust 087582/Z/08/Z
6 · The paper itself

Abstract

Cell division across members of the protozoan parasite phylum Apicomplexa displays a surprising diversity between different species as well as between different life stages of the same parasite. In most cases, infection of a host cell by a single parasite results in the formation of a polyploid cell from which individual daughters bud in a process dependent on a final round of mitosis. Unlike other apicomplexans, Toxoplasma gondii divides by a binary process consisting of internal budding that results in only two daughter cells per round of division. Since T. gondii is experimentally accessible and displays the simplest division mode, it has manifested itself as a model for apicomplexan daughter formation. Here, we review newly emerging insights in the prominent role that assembly of the cortical cytoskeletal scaffold plays in the process of daughter parasite formation.

Indexed as

Cell DivisionAnimalsCytoskeletonLife Cycle StagesToxoplasma

Identifiers

PMID22878103
PMCPMC4066374
OpenAlexW64164947

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.