Evidence map›Paper›PMID 22878023›Full record

Trial reportThe Lancet. Infectious diseases2012

Prevalences of sexually transmitted infections in young adults and female sex workers in Peru: a national population-based survey.

César P Cárcamo, Pablo E Campos, Patricia J García, James P Hughes, Geoff P Garnett, King K Holmes, Peru PREVEN study team

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in The Lancet. Infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 7 pooled it
33.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 7 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
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  11. Article
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  14. High-Risk Sexual Behaviors and Health Services Needs Among Bisexual Men in Peru: A Cross-Sectional Study.International journal of sexual health : official journal of the World Association for Sexual Health · 2025
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  15. Article
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  17. Review
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  19. Extra-genitalInternational journal of STD & AIDS · 2023
    Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

César P CárcamoEpidemiology, STD, and HIV Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Pablo E Campos
Patricia J García
James P Hughes
Geoff P Garnett
King K Holmes
Peru PREVEN study team
Universidad Peruana Cayetano Heredia · PEUniversity of Washington · USAIDS United · USBill & Melinda Gates Foundation · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
University of Washington STI-TM Cooperative Research CtrU19AI031448 · NIAID · UNIVERSITY OF WASHINGTON · PI HOLMES, KING K. · 1995 to 2010
$15.2M
UNIVERSITY OF WASHINGTON STD COOPERATIVE RESEARCH CENTERU01AI031448 · NIAID · UNIVERSITY OF WASHINGTON · PI HOLMES, KING KENNARD · 1991 to 1994
–
NIAID NIH HHS AI31448NIAID NIH HHS P30 AI027757NIAID NIH HHS P30-AI027757NIAID NIH HHS U19 AI031448Wellcome TrustWellcome Trust 059131/Z/99/ZWellcome Trust 078835/Z/05/BWellcome Trust 078835/Z/05/Z
6 · The paper itself

Abstract

backgroundWe assessed prevalences of seven sexually transmitted infections (STIs) in Peru, stratified by risk behaviours, to help to define care and prevention priorities.

methodsIn a 2002 household-based survey of the general population, we enrolled randomly selected 18-29-year-old residents of 24 cities with populations greater than 50 000 people. We then surveyed female sex workers (FSWs) in these cities. We gathered data for sexual behaviour; vaginal specimens or urine for nucleic acid amplification tests for Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis; and blood for serological tests for syphilis, HIV, and (in subsamples) herpes simplex virus 2 (HSV2) and human T-lymphotropic virus. This study is a registered component of the PREVEN trial, number ISRCTN43722548.

findings15 261 individuals from the general population and 4485 FSWs agreed to participate in our survey. Overall prevalence of infection with HSV2, weighted for city size, was 13·5% in men, 13·6% in women, and 60·6% in FSWs (all values in FSWs standardised to age composition of women in the general population). The prevalence of C trachomatis infection was 4·2% in men, 6·5% in women, and 16·4% in FSWs; of T vaginalis infection was 0·3% in men, 4·9% in women, and 7·9% in FSWs; and of syphilis was 0·5% in men, 0·4% in women, and 0·8% in FSWs. N gonorrhoeae infection had a prevalence of 0·1% in men and women, and of 1·6% in FSWs. Prevalence of HIV infection was 0·5% in men and FSWs, and 0·1% in women. Four (0·3%) of 1535 specimens were positive for human T-lymphotropic virus 1. In men, 65·0% of infections with HIV, 71·5% of N gonorrhoeae, and 41·4% of HSV2 and 60·9% of cases of syphilis were in the 13·3% who had sex with men or unprotected sex with FSWs in the past year. In women from the general population, 66·7% of infections with HIV and 16·7% of cases of syphilis were accounted for by the 4·4% who had been paid for sex by any of their past three partners.

interpretationDefining of high-risk groups could guide targeting of interventions for communicable diseases-including STIs-in the general Peruvian population.

fundingWellcome Trust-Burroughs Wellcome Fund Infectious Disease Initiative and US National Institutes of Health.

Indexed as

AdolescentAdultAntibodies, ViralChlamydia InfectionsFemaleGonorrheaHealth SurveysHerpes SimplexHerpesvirus 2, HumanHIV InfectionsHTLV-I InfectionsHumansMalePeruPrevalenceSexual BehaviorAntibodies, Viral

Identifiers

PMID22878023
PMCPMC3459082
OpenAlexW2097537105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.