Evidence map›Paper›PMID 22877562›Full record

ArticleEpidemiology and infection2013

Molecular epidemiology and clinical manifestations of human cryptosporidiosis in Sweden.

M Insulander, C Silverlås, M Lebbad, L Karlsson, J G Mattsson, B Svenungsson

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 172 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Therapeutic effects of acetylspiramycin and garlicin on cryptosporidiosis among drug users.International journal for parasitology. Drugs and drug resistance · 2015
    Trial
  4. Trial
  5. Article
  6. Article
  7. ConcurrentEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
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  9. Article
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  11. Emerging microbes & infections · 2024
    Article
  12. Outbreak of the novelEpidemiology and infection · 2024
    Article
  13. Review
  14. Rodent-adaptedOne health (Amsterdam, Netherlands) · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Current research in parasitology & vector-borne diseases · 2023
    Review
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

M InsulanderDepartment of Communicable Disease Control and Prevention, Stockholm County, Sweden.
C Silverlås
M Lebbad
L Karlsson
J G Mattsson
B Svenungsson
Karolinska Institutet · SEKarolinska University Hospital · SEStockholm County Council · SESwedish Institute · SESwedish University of Agricultural Sciences · SESwedish Veterinary Agency · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes the epidemiology and symptoms in 271 cryptosporidiosis patients in Stockholm County, Sweden. Species/genotypes were determined by polymerase chain reaction-restriction fragment-length polymorphism (PCR-RFLP) of the Cryptosporidium oocyst wall protein (COWP) and 18S rRNA genes. Species were C. parvum (n=111), C. hominis (n=65), C. meleagridis (n=11), C. felis (n=2), Cryptosporidium chipmunk genotype 1 (n=2), and a recently described species, C. viatorum (n=2). Analysis of the Gp60 gene revealed five C. hominis allele families (Ia, Ib, Id, Ie, If), and four C. parvum allele families (IIa, IIc, IId, IIe). Most C. parvum cases (51%) were infected in Sweden, as opposed to C. hominis cases (26%). Clinical manifestations differed slightly by species. Diarrhoea lasted longer in C. parvum cases compared to C. hominis and C. meleagridis cases. At follow-up 25-36 months after disease onset, 15% of the patients still reported intermittent diarrhoea. In four outbreaks and 13 family clusters, a single subtype was identified, indicating a common infection source, which emphasizes the value of genotyping for epidemiological investigations.

Indexed as

AdolescentAdultAgedChildChild, PreschoolCluster AnalysisCryptosporidiosisCryptosporidiumDiarrheaDisease OutbreaksFamilyFemaleGenotypeHumansInfantMale

Identifiers

PMID22877562
PMCPMC9151846
OpenAlexW2107017594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.