ReviewBioanalysis2012
Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders.
Review in Bioanalysis, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease.Translational stroke research · 2021Pooled it
- Gradient Scheme Optimization for PRESS-Localized Edited MRS Using Weighted Pathway Suppression.NMR in biomedicine · 2026Article
- Meta-analysis ofPCN reports : psychiatry and clinical neurosciences · 2025Article
- Gradient scheme optimization for PRESS-localized edited MRS using weighted pathway suppression.bioRxiv : the preprint server for biology · 2025Article
- Next-generation biomarkers for alcohol consumption and alcohol use disorder diagnosis, prognosis, and treatment: A critical review.Alcohol, clinical & experimental research · 2025Review
- Statistical Optimization of Culture Conditions for Enhanced Biomass Yield ofInternational journal of food science · 2025Article
- Altered prefrontal neurochemistry in the DJ-1 knockout mouse model of Parkinson's disease: complementary semi-quantitative analyses with in vivo magnetic resonance spectroscopy and MALDI-MSI.Analytical and bioanalytical chemistry · 2022Article
- MR Spectroscopy of the Insula: Within- and between-Session Reproducibility of MEGA-PRESS Measurements of GABA+ and Other Metabolites.Brain sciences · 2021Article
- The Brain Metabolic Signature in Superagers Using In VivoAJNR. American journal of neuroradiology · 2021Article
- Effect of Lacosamide and Ethosuximide Chronic Treatment on Neural Precursor Cells and Cognitive Functions after Pilocarpine Induced Status Epilepticus in Mice.Brain sciences · 2021Article
- γ-aminobutyric acid and glutamate/glutamine alterations of the left prefrontal cortex in individuals with methamphetamine use disorder: a combined transcranial magnetic stimulation-magnetic resonance spectroscopy study.Annals of translational medicine · 2020Article
- Aripiprazole and Riluzole treatment alters behavior and neurometabolites in young ADHD rats: a longitudinalTranslational psychiatry · 2017Article
- Can Neuroimaging Provide Reliable Biomarkers for Obsessive-Compulsive Disorder? A Narrative Review.Current psychiatry reports · 2016Review
- Review
- Neuropharmacological and neurobiological relevance of in vivo ¹H-MRS of GABA and glutamate for preclinical drug discovery in mental disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Article
- High-field proton magnetic resonance spectroscopy reveals metabolic effects of normal brain aging.Neurobiology of aging · 2014Article
- Moderate relationships between NAA and cognitive ability in healthy adults: implications for cognitive spectroscopy.Frontiers in human neuroscience · 2014Article
- Alzheimer's disease biomarkers in animal models: closing the translational gap.American journal of neurodegenerative disease · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The ongoing development of animal models of neurological and psychiatric disorders in combination with the development of advanced nuclear magnetic resonance (NMR) techniques and instrumentation has led to increased use of in vivo proton NMR spectroscopy ((1)H-MRS) for neurochemical analyses. (1)H-MRS is one of only a few analytical methods that can assay in vivo and longitudinal neurochemical changes associated with neurological and psychiatric diseases, with the added advantage of being a technique that can be utilized in both preclinical and clinical studies. In this review, recent progress in the use of (1)H-MRS to investigate animal models of neurological and psychiatric disorders is summarized with examples from the literature and our own work.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.