Evidence map›Paper›PMID 22876351›Full record

ArticleBiomedical optics express2012

Dual-mode laparoscopic fluorescence image-guided surgery using a single camera.

Daniel C Gray, Evgenia M Kim, Victoria E Cotero, Anshika Bajaj, V Paul Staudinger, Cristina A Tan Hehir, Siavash Yazdanfar

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Biomedical optics express · 2017
    Article
  4. Review
  5. Article
  6. Fluorescence Phenomena in Nerve-Labeling Styryl-Type Dyes.Journal of photochemistry and photobiology. A, Chemistry · 2016
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Identification of the protein target of myelin-binding ligands by immunohistochemistry and biochemical analyses.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2013
    Article
  12. Article
  13. Fluorescence imaging in surgery.IEEE reviews in biomedical engineering · 2013
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Daniel C GrayGE Global Research, One Research Circle, Niskayuna, NY, 12309, USA.
Evgenia M Kim
Victoria E Cotero
Anshika Bajaj
V Paul Staudinger
Cristina A Tan Hehir
Siavash Yazdanfar
General Electric (United States) · US

Funding

Targeted Fluorescence Imaging of Nerves for Surgical GuidanceR01EB011872 · NIBIB · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI TAN HEHIR, CRISTINA A · 2010 to 2013
$3.6M
Neural mechanisms and behavioral consequences of non-Gaussian likelihoods in sensorimotor learningR01EB022872 · NIBIB · EMORY UNIVERSITY · PI NEMENMAN, ILYA M., SOBER, SAMUEL · 2016 to 2018
$1.2M
NIBIB NIH HHS R01 EB011872NIBIB NIH HHS R01 EB022872
6 · The paper itself

Abstract

Iatrogenic nerve damage is a leading cause of morbidity associated with many common surgical procedures. Complications arising from these injuries may result in loss of function and/or sensation, muscle atrophy, and chronic neuropathy. Fluorescence image-guided surgery offers a potential solution for avoiding intraoperative nerve damage by highlighting nerves that are otherwise difficult to visualize. In this work we present the development of a single camera, dual-mode laparoscope that provides near simultaneous display of white-light and fluorescence images of nerves. The capability of the instrumentation is demonstrated through imaging several types of in situ rat nerves via a nerve specific contrast agent. Full color white light and high brightness fluorescence images and video of nerves as small as 100 µm in diameter are presented.

Indexed as

(170.2150) Endoscopic imaging(170.3880) Medical and biological imaging(300.2530) Fluorescence, laser-induced

Identifiers

PMID22876351
PMCPMC3409706
OpenAlexW2010596227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.