Evidence map›Paper›PMID 22876236›Full record

ArticleFrontiers in psychology2012

Diagnosing medication non-adherence in a patient with myocardial infarction.

Siqin Ye, David J Krupka, Karina W Davidson

Abstract read
In one paragraph

Article in Frontiers in psychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Siqin YeCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center New York, NY, USA.
David J Krupka
Karina W Davidson

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
POSTDOCTORAL TRAINING IN CARDIOVASCULAR DISEASET32HL007854 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Marwah Abdalla, Michael Argenziano · 1996 to 2026
$14.7M
Depression, Biobehavioral Mechanisms, & CHD/Mortality OutcomesP01HL088117 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2008 to 2013
$12.5M
Depression Screening RCT in ACS patients: Quality of Life and Cost OutcomesR01HL114924 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KRONISH, IAN MATTHEW · 2013 to 2017
$4.2M
Comparison of Depression Interventions after Acute Coronary Syndrome (CODIACS)RC2HL101663 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2009 to 2010
$4.1M
Midcareer Mentoring in Behavioral Cardiology: Depression & Cardiovascular DiseaseK24HL084034 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2006 to 2015
$1.6M
NCRR NIH HHS UL1 RR024156NHLBI NIH HHS K24 HL084034NHLBI NIH HHS P01 HL088117NHLBI NIH HHS R01 HL114924NHLBI NIH HHS RC2 HL101663NHLBI NIH HHS T32 HL007854
6 · The paper itself

Abstract

backgroundMedication non-adherence continues to be a major challenge facing the healthcare system. A case is presented of a 48-year-old man with myocardial infarction who was found to be non-adherent to multiple medications. Conceptual models are reviewed along with current approaches for assessment and treatment of medication non-adherence.

designCase report and literature review. DISCUSSION: A theoretical model for medication non-adherence built on the Theory of Planned Behavior is presented. Empirical evidence is reviewed for determinants of non-adherent behavior such as health beliefs and self-efficacy. Current methods to assess medication non-adherence, including self-report, pill count, biological drug levels, pharmacy refill, and electronic bottles are summarized along with their limitations. Finally, an individualized approach for assessment is described using the case presented and the conceptual framework outlined above. Follow-up for the patient and potential interventions to improve medication adherence are discussed.

conclusionDespite the challenges, a conceptual framework for medication non-adherence can guide assessment and treatment. Further research for innovative and effective methods to detect and treat medication non-adherence is urgently needed to aid clinicians in treating this pervasive behavioral problem.

Indexed as

assessmentcardiovascular diseaseschronic disease managementmedication non-adherence

Identifiers

PMID22876236
PMCPMC3411184

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.