ArticleEuropean journal of organic chemistry2012
Asymmetric Methods for the Synthesis of Flavanones, Chromanones, and Azaflavanones.
Article in European journal of organic chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Photochemical Deracemization of Chromanes and its Application to the Synthesis of Enantiopure Bioactive Compounds.Angewandte Chemie (International ed. in English) · 2026Article
- Hydrogen-deuterium exchange reveals catalytically linked protein flexibility in myoglobin-mediated intramolecular C(spProtein science : a publication of the Protein Society · 2026Article
- A planar chiral organoselenium enabled enantioselective intramolecular oxidation of trisubstituted olefins.Nature communications · 2025Article
- Electrochemically Induced, Metal Free Synthesis of 2-substituted chroman-4-ones.ChemistryOpen · 2025Article
- Polyphenols and post-exercise muscle damage: a comprehensive review of literature.European journal of medical research · 2025Review
- Enantioselective Synthesis of Aza-Flavanones with an All-Carbon Quaternary Stereocenter via NHC-Catalyzed Intramolecular Annulation.ACS omega · 2023Article
- Highly Enantioselective Catalytic Alkynylation of Quinolones: Substrate Scope, Mechanistic Studies, and Applications in the Syntheses of ChiralACS catalysis · 2023Article
- Bioactivity, Molecular Mechanism, and Targeted Delivery of Flavonoids for Bone Loss.Nutrients · 2023Review
- Enantioselective, Decarboxylative (3+2)-Cycloaddition of Azomethine Ylides and Chromone-3-Carboxylic Acids.Molecules (Basel, Switzerland) · 2022Article
- Enantioselective Dearomative Alkynylation of Chromanones: Opportunities and Obstacles.Synthesis · 2022Article
- Synthesis and Stereochemical Characterization of a Novel Chiral α-Tetrazole Binaphthylazepine Organocatalyst.Molecules (Basel, Switzerland) · 2022Article
- Visible Light-Driven Reductive Azaarylation of Coumarin-3-carboxylic Acids.The Journal of organic chemistry · 2022Article
- Redox-neutral and metal-free synthesis of 3-(arylmethyl)chroman-4-onesFrontiers in chemistry · 2022Article
- Doubly Decarboxylative Synthesis of 4-(Pyridylmethyl)chroman-2-ones and 2-(Pyridylmethyl)chroman-4-ones under Mild Reaction Conditions.Molecules (Basel, Switzerland) · 2021Article
- Insights on a new sulfonamide chalcone with potential antineoplastic application.Journal of molecular modeling · 2021Article
- Robust, Enantioselective Construction of Challenging, Biologically Relevant Tertiary Ether Stereocenters.ACS catalysis · 2021Article
- Catalytic enantioselective synthesis of tetrasubstituted chromanonesChemical science · 2020Article
- Copper Bis(oxazoline)-Catalyzed Enantioselective Alkynylation of Benzopyrylium Ions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Synthesis and Anticancer Activity of Structure Simplified Naturally-Inspired Dimeric Chromenone Derivatives.European journal of organic chemistry · 2019Article
- Enantioselective Synthesis of Chromanones Bearing an α,α-Disubstituted α-Amino Acid Moiety via Decarboxylative Michael Reaction.Molecules (Basel, Switzerland) · 2019Article
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Authors and funding
2 authors.
Funding
Abstract
Flavanones, chromanones, and related structures are privileged natural products that display a wide variety of biological activities. Although flavanoids are abundant in nature, there are a limited number of available general and efficient synthetic methods for accessing molecules of this class in a stereoselective manner. Their structurally simple architectures belie the difficulties involved in installation and maintenance of the stereogenic configuration at the C2 position, which can be sensitive and can undergo epimerization under mildly acidic, basic, and thermal reaction conditions. This review presents the methods currently used to access these related structures. The synthetic methods include manipulation of the flavone/flavanone core, carbon-carbon bond formation, and carbon-heteroatom bond formation.
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