ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Organization of cerebral projections to identified cerebellar zones in the posterior cerebellum of the rat.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- Social cognition and the cerebellum: A meta-analytic connectivity analysis.Human brain mapping · 2015Pooled it
- Viral Tracing Gone Viral: Expanded Possibilities Call for Increased Caution in Describing Cerebellar Network Connections.Cerebellum (London, England) · 2026Review
- The cerebellum exploits a thalamic carrier frequency to refine motor behaviors.bioRxiv : the preprint server for biology · 2026Article
- Anatomy of Cerebro-cerebellar Circuits in Motor Control.Cerebellum (London, England) · 2026Review
- The cerebellar involvement in essential tremor: the connecting roads.Arquivos de neuro-psiquiatria · 2025Review
- Cerebellar Crus II Regulates Recognition and Spatial Memory in Mice.Molecular neurobiology · 2025Article
- Whisker pad stimulation with different frequencies reveals non-uniform modulation of functional MRI signal across sensory systems in awake rats.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Functional recruitment and connectivity of the cerebellum is associated with the emergence of Theory of Mind in early childhood.Nature communications · 2025Article
- Cerebral cortical functional hyperconnectivity in a mouse model of spinocerebellar ataxia type 8 (SCA8).Neurobiology of disease · 2025Article
- Human cerebellum and social navigation: cerebello-cerebral connectivity using dynamic causal modelling.Social cognitive and affective neuroscience · 2025Article
- Distinct impact modes of polygenic disposition to dyslexia in the adult brain.Science advances · 2024Article
- Clinical Heterogeneity of Essential Tremor: Understanding Neural Substrates of Action Tremor Subtypes.Cerebellum (London, England) · 2024Review
- Altered prefrontal and cerebellar parvalbumin neuron counts are associated with cognitive changes in male rats.Experimental brain research · 2024Article
- Cerebral cortical functional hyperconnectivity in a mouse model of spinocerebellar ataxia type 8 (SCA8).bioRxiv : the preprint server for biology · 2024Article
- Cerebellum Lecture: the Cerebellar Nuclei-Core of the Cerebellum.Cerebellum (London, England) · 2024Review
- A cerebro-cerebellar network for learning visuomotor associations.Nature communications · 2024Article
- Reduced Cerebellar Brain Inhibition and Vibrotactile Perception in Response to Mechanical Hand Stimulation at Flutter Frequency.Cerebellum (London, England) · 2024Article
- Article
- Effective cerebello-cerebral connectivity during implicit and explicit social belief sequence learning using dynamic causal modeling.Social cognitive and affective neuroscience · 2023Article
- A disynaptic basal ganglia connection to the inferior olive: potential for basal ganglia influence on cerebellar learning.Frontiers in systems neuroscience · 2023Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cerebrocerebellar connection makes use of two of the largest fiber tracts in the mammalian brain, i.e., the cerebral and medial cerebellar peduncles. Neuroanatomical approaches aimed to elucidate the organization of this important connection have been hindered by its multisynaptic nature, the complex organization of its components, and the dependency of conventional tracers on precisely placed injections. To overcome these problems, we used rabies virus (RV) as a retrograde transneuronal tracer. RV was injected simultaneously with cholera toxin β subunit (CTb) into selected areas of the cerebellar cortex of 18 male Wistar rats. A survival time of 48-50 h resulted in first- and second-order labeling of RV in combination with first-order labeling of CTb. The distribution of CTb-labeled neurons in the inferior olive established the zonal identity of the injection site. In this way, it was possible to examine the cortical distribution of neurons from which disynaptic cerebrocerebellar projections to specific cerebellar loci originate. The results show that this distribution covaries with the identity of the injected cerebellar lobule. More subtle changes were present when different zones of the same lobule were injected. The C1 zone of lobule VIII receives a more prominent projection from the somatosensory cortex compared with the C2/D zones. The laterally positioned D zones receive information from more rostral regions of the cerebral cortex. The vermis of lobule VII receives a prominent input from the retrosplenial and orbitofrontal cortices. Different injection sites also result in differences in laterality of the connections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.