ReviewJournal of neural transmission (Vienna, Austria : 1996)2012
Does structural neuroimaging reveal a disturbance of iron metabolism in Parkinson's disease? Implications from MRI and TCS studies.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Targeting chelatable iron as a therapeutic modality in Parkinson's disease.Antioxidants & redox signaling · 2014Trial
- High correlation of quantitative susceptibility mapping and echo intensity measurements of nigral iron overload in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Nigral ATP13A2 depletion induces Parkinson's disease-related neurodegeneration in a pilot study in non-human primates.NPJ Parkinson's disease · 2024Article
- Blood-brain barrier alterations and their impact on Parkinson's disease pathogenesis and therapy.Translational neurodegeneration · 2024Review
- Lactoferrin: from the structure to the functional orchestration of iron homeostasis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Review
- Susceptibility Magnetic Resonance Imaging Correlates with Glial Density and Tau in the Substantia Nigra Pars Compacta.Movement disorders : official journal of the Movement Disorder Society · 2023Article
- Evaluation of ferritin and TfR level in plasma neural-derived exosomes as potential markers of Parkinson's disease.Frontiers in aging neuroscience · 2023Article
- Ginsenoside Rg1 Plays a Neuroprotective Role in Regulating the Iron-Regulated Proteins and Against Lipid Peroxidation in Oligodendrocytes.Neurochemical research · 2022Article
- Neuroprotective Activities of Curcumin in Parkinson's Disease: A Review of the Literature.International journal of molecular sciences · 2021Review
- Time-Specific Pattern of Iron Deposition in Different Regions in Parkinson's Disease Measured by Quantitative Susceptibility Mapping.Frontiers in neurology · 2021Article
- Brain iron deposition is linked with cognitive severity in Parkinson's disease.Journal of neurology, neurosurgery, and psychiatry · 2020Article
- Signal Alteration of Substantia Nigra on 3.0T Susceptibility-weighted Imaging in Parkinson's Disease and Vascular Parkinsonism.Current medical science · 2019Article
- Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration.The American journal of pathology · 2019Article
- Shifted dynamic interactions between subcortical nuclei and inferior frontal gyri during response preparation in persistent developmental stuttering.Brain structure & function · 2018Article
- Bioavailable Trace Metals in Neurological Diseases.Current treatment options in neurology · 2016Review
- The role of iron in brain ageing and neurodegenerative disorders.The Lancet. Neurology · 2014Review
- Article
- Iron metabolism in the CNS: implications for neurodegenerative diseases.Nature reviews. Neuroscience · 2013Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A central role of iron in the pathogenesis of Parkinson's disease (PD) has been discussed for many years. Numerous studies using magnetic resonance imaging and transcranial sonography have been performed to detect alterations in tissue iron content of the substantia nigra. This manuscript reviews the findings of this still controversial issue and indicates that specific abnormalities that are suggested to be related to a disturbance of iron homeostasis may play an early role in the pathogenesis of PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.