ArticleEuropean journal of nuclear medicine and molecular imaging2012
Stress-induced myocardial ischemia is associated with early post-stress left ventricular mechanical dyssynchrony as assessed by phase analysis of 201Tl gated SPECT myocardial perfusion imaging.
Article in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Prognostic value of left ventricular mechanical dyssynchrony indices derived from gated myocardial perfusion SPECT in coronary artery disease: a systematic review and meta-analysis.Annals of nuclear medicine · 2024Pooled it
- Mechanical dyssynchrony and diastolic dysfunction are common in LVH: a pilot correlation study using Doppler echocardiography and CZT gated-SPECT MPI.Scientific reports · 2018Trial
- Effects of stress on myocardial perfusion and left ventricular synchrony in patients undergoing left bundle branch area pacing.European journal of nuclear medicine and molecular imaging · 2026Article
- Assessing the diagnostic value of left ventricular synchrony indices derived from phase analysis by D-SPECT in identifying obstructive coronary artery disease.The international journal of cardiovascular imaging · 2024Article
- Contractile asymmetry and survival in patients with left bundle branch abnormality treated with cardiac resynchronization therapy.European heart journal. Imaging methods and practice · 2023Article
- Left ventricular mechanical dyssnchrony: A potential new marker for 3-vessel CAD.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Evaluation of dyssynchrony with nuclear cardiac imaging: New evidence for an old parameter.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Optimizing diagnosis and risk stratification of ischemic heart disease by myocardial perfusion imaging: The incremental values of non-perfusion variables during vasodilator stress.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Left ventricular mechanical dyssynchrony in patients with chest pain and normal epicardial coronary arteries.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Left ventricular regional asynchrony: Earliest marker for ischemic cardiomyopathy?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Impact of early post-stressThe international journal of cardiovascular imaging · 2021Article
- Comparison of left ventricular mechanical dyssynchrony parameters between exercise and adenosine triphosphate stress tests using gated single-photon emission computed tomography myocardial perfusion imaging.Kardiologia polska · 2021Article
- A perfect tool for comprehensive evaluation of myocardial perfusion and function: Stress PET imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Auxiliary ischemic markers, the role of left ventricular dyssynchrony.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Ventricular synchrony is not significantly determined by absolute myocardial perfusion in patients with chronic heart failure: AJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Dyssynchrony as a marker of adverse prognosis among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Is myocardial viability related to left ventricular dyssynchrony?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Could myocardial viability be related to left ventricular dyssynchrony? Simultaneous evaluation by gated SPECT-MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- The clinical usefulness of phase analysis in detecting coronary artery disease using dipyridamole thallium-201-gated myocardial perfusion imaging with a cadmium-zinc-telluride camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Left ventricular mechanical dyssynchrony for CAD diagnosis: Does it have incremental clinical values?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeIn (201)Tl SPECT myocardial perfusion imaging (MPI) data are acquired shortly after the stress injection to assess early post-stress left ventricle (LV) function. The purpose of this study was to use (201)Tl SPECT MPI to investigate whether stress-induced myocardial ischemia is associated with LV mechanical dyssynchrony.
methodsEnrolled in the study were 75 patients who were referred for dipyridamole stress and rest (201)Tl gated SPECT MPI. The early post-stress scan was started 5 min after injection, and followed by the rest scan 4 h later. The patients were divided into three groups: ischemia group (N = 25, summed stress score, SSS, ≥5, summed rest score, SRS, <5), infarct group (N = 16, SSS ≥5, SRS ≥5) and normal group (N = 34, SSS <5, SRS <5). LV dyssynchrony parameters were calculated by phase analysis, and compared between the stress and rest images.
resultsIn the ischemia group, LV dyssynchrony was significantly larger during stress than during rest. On the contrary, LV dyssynchrony during stress was significantly smaller than during rest in the normal and infarct groups. LV dyssynchrony during rest was significantly larger in the infarct group than in the normal and ischemia groups. There were no significant differences in LV dyssynchrony during rest between the normal and ischemia groups.
conclusionStress-induced myocardial ischemia caused dyssynchronous contraction in the ischemic region, leading to a deterioration in LV synchrony. Normal myocardium had more synchronous contraction during stress. The different dyssynchrony pattern between ischemic and normal myocardium early post-stress may aid the diagnosis of coronary artery disease using (201)Tl gated SPECT MPI.
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