Evidence map›Paper›PMID 22875288›Full record

ArticleCurrent rheumatology reports2012

Cocaine-induced vasculitis: clinical and immunological spectrum.

Luis R Espinoza, Rodolfo Perez Alamino

Abstract read
PubMed Publisher
In one paragraph

Article in Current rheumatology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. When recreation turns risky: the multifaceted negative impact of cocaine-induced nasal septal perforations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
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  10. Nephrotoxic effects of common and emerging drugs of abuse.Clinical journal of the American Society of Nephrology : CJASN · 2014
    Review
  11. Stimulants and the lung : review of literature.Clinical reviews in allergy & immunology · 2014
    Review
  12. Cocaine-induced leg ulceration.BMJ case reports · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Luis R EspinozaRheumatology Section, Department of Internal Medicine, LSU Health Sciences Center, New Orleans, LA 70112-2822, USA. lespin1@lsuhsc.edu
Rodolfo Perez Alamino
Louisiana State University Health Sciences Center New Orleans · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Levamisole-contaminated cocaine has recently been recognized in North America and Europe, and its use is associated with a variety of clinical and autoimmune abnormalities. The clinical characteristic seems to be the presence of a painful purpuric skin rash that predominantly affects the ear lobes and cheeks, often accompanied by systemic manifestations including fever, malaise, arthralgias, myalgias, and laboratory abnormalities, for example leukopenia, neutropenia, positive ANA, ANCA, and phospholipid antibodies. Most of these manifestations can be seen with the use of either drug, especially levamisole. There is no specific therapy, and discontinuation of its use is followed by improvement. Prednisone and immunosuppressive therapy may be needed at times. Further use of the drug is characterized by recurrence of most of the complaints.

Indexed as

Adjuvants, ImmunologicAgranulocytosisAntibodies, Antineutrophil CytoplasmicCocaineCocaine-Related DisordersDrug ContaminationHumansLevamisoleVasculitisVasoconstrictor AgentsAdjuvants, ImmunologicAntibodies, Antineutrophil CytoplasmicCocaineLevamisoleVasoconstrictor Agents

Identifiers

PMID22875288
OpenAlexW2142154476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.