ArticleNeurology2012
Prevalence and significance of stroke symptoms among patients receiving maintenance dialysis.
Article in Neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Prevalence of stroke among patients with chronic kidney disease, Taif, Saudi Arabia.Saudi medical journal · 2023Article
- Stroke Subtype Among Individuals With Chronic Kidney Disease.Canadian journal of kidney health and disease · 2023Article
- Impact of multimorbidity on risk and outcome of stroke: Lessons from chronic kidney disease.International journal of stroke : official journal of the International Stroke Society · 2021Article
- Cognitive interventions for adults with chronic kidney disease: protocol for a scoping review.Systematic reviews · 2020Article
- Serum klotho: a potential predictor of cerebrovascular disease in hemodialysis patients.BMC nephrology · 2019Article
- The metabolomic quest for a biomarker in chronic kidney disease.Clinical kidney journal · 2018Article
- Article
- Stroke risk and outcomes in patients with chronic kidney disease or end-stage renal disease: Two nationwide studies.PloS one · 2018Article
- Loss of executive function after dialysis initiation in adults with chronic kidney disease.Kidney international · 2017Observational
- Metabolic Profiling of Impaired Cognitive Function in Patients Receiving Dialysis.Journal of the American Society of Nephrology : JASN · 2016Article
- Stroke Symptoms With Absence of Recognized Stroke Are Associated With Cognitive Impairment and Depressive Symptoms in Older Adults With Diabetes.Journal of geriatric psychiatry and neurology · 2016Article
- Prevalence and correlates of functional dependence among maintenance dialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2015Article
- Development and validation of a short-version checklist for patients undergoing hemodialysis based on the International Classification of Functioning, Disability and Health.Clinical and experimental nephrology · 2015Article
- Quantitative measurement of brain iron deposition in patients with haemodialysis using susceptibility mapping.Metabolic brain disease · 2015Article
- Patient-reported cognitive functioning and daily functioning in chronic dialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2015Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this cross-sectional study was to determine the prevalence and potential significance of stroke symptoms among end-stage renal disease (ESRD) patients without a prior diagnosis of stroke or TIA.
methodsWe enrolled 148 participants with ESRD from 5 clinics. Stroke symptoms and functional status, basic and instrumental activities of daily living (ADL, IADL), were ascertained by validated questionnaires. Cognitive function was assessed with a neurocognitive battery. Cognitive impairment was defined as a score 2 SDs below norms for age and education in 2 domains. IADL impairment was defined as needing assistance in at least 1 of 7 IADLs.
resultsAmong the 126 participants without a prior stroke or TIA, 46 (36.5%) had experienced one or more stroke symptoms. After adjustment for age, sex, race, education, language, diabetes, and cardiovascular disease, participants with stroke symptoms had lower scores on tests of attention, psychomotor speed, and executive function, and more pronounced dependence in IADLs and ADLs (p ≤ 0.01 for all). After adjustment for age, sex, race, education, language, diabetes, and cardiovascular disease, participants with stroke symptoms had a higher likelihood of cognitive impairment (odds ratio [OR] 2.47, 95% confidence interval [CI] 1.03-5.92) and IADL impairment (OR 3.86, 95% CI 1.60-9.28).
conclusionsStroke symptoms are common among patients with ESRD and strongly associated with impairments in cognition and functional status. These findings suggest that clinically significant stroke events may go undiagnosed in this high-risk population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.