ArticleEpidemiology and infection2013
Modelling pertussis transmission to evaluate the effectiveness of an adolescent booster in Argentina.
Article in Epidemiology and infection, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Pertussis epidemiology in Argentina: TRENDS after the introduction of maternal immunisation.Epidemiology and infection · 2018Article
- Infection-acquired versus vaccine-acquired immunity in an SIRWS model.Infectious Disease Modelling · 2018Article
- Evaluation of outbreak response immunization in the control of pertussis using agent-based modeling.PeerJ · 2016Article
- Strategies and new developments to control pertussis, an actual health problem.Pathogens and disease · 2015Review
- Pertussis re-emergence in the post-vaccination era.BMC infectious diseases · 2013Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the current epidemiological situation of pertussis, several countries have implemented vaccination strategies that include a booster dose for adolescents. Since there is still no evidence showing that the adolescent booster has a positive effect on the most vulnerable group represented by infants, it is difficult to universalize the recommendation to include such reinforcement. In this work we present an age-structured compartmental deterministic model that considers the outstanding epidemiological features of the disease in order to assess the impact of the booster dose at age 11 years (Tdap booster) to infants. To this end, we performed different parameterizations of the model that represent distinct possible epidemiological scenarios. The results obtained show that the inclusion of a single Tdap dose at age 11 years significantly reduces the incidence of the disease within this age group, but has a very low impact on the risk group (0-1 year). An effort to improve the coverage of the first dose would have a much greater impact on infants. These results hold in the 18 scenarios considered, which demonstrates the robustness of these conclusions.
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