ReviewLipids in health and disease2012
Arachidonic acid metabolites in pathogenic yeasts.
Review in Lipids in health and disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Vascular Notch-Related Protein Expression in a Rat Model of Central Venous Catheter-AssociatedPathogens (Basel, Switzerland) · 2026Article
- Targeted Metabolomics Resolves Amino Acid and Lipid Specialization Between Pileus and Stipe in Artificially CultivatedLife (Basel, Switzerland) · 2026Article
- Improved de novo production of prostaglandin FCommunications biology · 2026Article
- Thermotolerant insect-associated selective pressure may drive increased lipid metabolic plasticity and emerging pathogenic potential in yeasts.Frontiers in microbiology · 2026Article
- Article
- Impact of interkingdom microbial interactions in the vaginal tract.PLoS pathogens · 2024Article
- The Synthesis of 3-(Molecules (Basel, Switzerland) · 2022Article
- Sperm-Guiding Unconventional Prostaglandins inMetabolites · 2021Review
- Complex and Controversial Roles of Eicosanoids in Fungal Pathogenesis.Journal of fungi (Basel, Switzerland) · 2021Review
- Eicosanoid production byVirulence · 2019Review
- Signature profile of cyclooxygenase-independent F2 series prostaglandins in C. elegans and their role in sperm motility.Scientific reports · 2019Article
- Genome sequence of the opportunistic human pathogen Magnusiomyces capitatus.Current genetics · 2019Article
- Prostaglandin EPharmacology & therapeutics · 2018Review
- A review on algae and plants as potential source of arachidonic acid.Journal of advanced research · 2018Review
- Nimesulide inhibits pathogenic fungi: PGE2-dependent mechanisms.Folia microbiologica · 2017Article
- Candida albicans and Pseudomonas aeruginosa Interaction, with Focus on the Role of Eicosanoids.Frontiers in physiology · 2016Review
- Candida parapsilosis produces prostaglandins from exogenous arachidonic acid and OLE2 is not required for their synthesis.Virulence · 2015Article
- Oxidized fatty acids as inter-kingdom signaling molecules.Molecules (Basel, Switzerland) · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although most of what is known about the biology and function of arachidonic acid metabolites comes from the study of mammalian biology, these compounds can also be produced by lower eukaryotes, including yeasts and other fungi. It is also in this group of organisms that the least is known about the metabolic pathways leading to the production of these compounds as well as the functions of these compounds in the biology of fungi and yeasts. This review will deal with the discovery of oxylipins from polyunsaturated fatty acids, and more specifically the arachidonic acid derived eicosanoids, such as 3-hydroxy eicosatetraenoic acid, prostaglandin F2α and prostaglandin E2, in yeasts starting in the early 1990s. This review will also focus on what is known about the metabolic pathways and/or proteins involved in the production of these compounds in pathogenic yeasts. The possible roles of these compounds in the biology, including the pathology, of these organisms will be discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.