Evidence map›Paper›PMID 22872477›Full record

ReviewAdvances in experimental medicine and biology2013

Meiotic development in Caenorhabditis elegans.

Doris Y Lui, Monica P Colaiácovo

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Therapeutic Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Article
  16. Tracing the Chromatin: From 3C to Live-Cell Imaging.Chemical & biomedical imaging · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Doris Y LuiDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Monica P Colaiácovo

Funding

Synaptonemal Complex Assembly and Function in MeiosisR01GM072551 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Monica P Colaiacovo · 2005 to 2026
$7.5M
NIGMS NIH HHS R01 GM072551NIGMS NIH HHS R01GM072551
6 · The paper itself

Abstract

Caenorhabditis elegans has become a powerful experimental organism with which to study meiotic processes that promote the accurate segregation of chromosomes during the generation of haploid gametes. Haploid reproductive cells are produced through one round of chromosome replication followed by two -successive cell divisions. Characteristic meiotic chromosome structure and dynamics are largely conserved in C. elegans. Chromosomes adopt a meiosis-specific structure by loading cohesin proteins, assembling axial elements, and acquiring chromatin marks. Homologous chromosomes pair and form physical connections though synapsis and recombination. Synaptonemal complex and crossover formation allow for the homologs to stably associate prior to remodeling that facilitates their segregation. This chapter will cover conserved meiotic processes as well as highlight aspects of meiosis that are unique to C. elegans.

Indexed as

AnimalsCaenorhabditis elegansMeiosis

Identifiers

PMID22872477
PMCPMC3764601

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.