ArticlePhysical biology2012
Weakly nonlinear analysis of symmetry breaking in cell polarity models.
Article in Physical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Non-asymptotic transients away from steady states determine cellular responsiveness to dynamic spatial-temporal signals.PLoS computational biology · 2023Article
- Article
- Cell polarisation in a bulk-surface model can be driven by both classic and non-classic Turing instability.NPJ systems biology and applications · 2021Article
- On system-spanning demixing properties of cell polarization.PloS one · 2019Article
- Spherical Caps in Cell Polarization.Biophysical journal · 2018Article
- Spatial modeling of the membrane-cytosolic interface in protein kinase signal transduction.PLoS computational biology · 2018Article
- Principles that govern competition or co-existence in Rho-GTPase driven polarization.PLoS computational biology · 2018Article
- Effects of 3D geometries on cellular gradient sensing and polarization.Physical biology · 2016Article
- Local perturbation analysis: a computational tool for biophysical reaction-diffusion models.Biophysical journal · 2015Article
- An efficient, nonlinear stability analysis for detecting pattern formation in reaction diffusion systems.Bulletin of mathematical biology · 2014Article
- A model for intracellular actin waves explored by nonlinear local perturbation analysis.Journal of theoretical biology · 2013Article
- Independence of symmetry breaking on Bem1-mediated autocatalytic activation of Cdc42.The Journal of cell biology · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Spontaneous symmetry breaking leading to polarization of the cell is a key step initiating many morphogenetic processes. In addition to experimental studies, model-based theoretical description helps to understand the conditions and limitations of this process. Such description is limited usually to linear stability analysis supplied by the numerical simulations to establish the dependence of the polarization dynamics on the model parameters. Here we describe the application of a powerful weakly nonlinear analysis method to a minimalistic model characterized by the conservation of mass of the protein governing the polarization dynamics.
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Registered trials
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