ReviewThe Kaohsiung journal of medical sciences2012
The association between phthalate exposure and asthma.
Review in The Kaohsiung journal of medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
- The effect of chronic inflammation on female fertility.Reproduction (Cambridge, England) · 2025Review
- Article
- Phthalate biomarkers and associations with respiratory symptoms and healthcare utilization among low-income urban children with asthma.Environmental research · 2022Article
- Are Phthalate Exposure Related to Oxidative Stress in Children and Adolescents with Asthma? A Cumulative Risk Assessment Approach.Antioxidants (Basel, Switzerland) · 2022Article
- The Role of PPAR-γ in Allergic Disease.Current allergy and asthma reports · 2021Review
- Occupational Hazards and Risks Associated with Phthalates among Slovakian Firefighters.International journal of environmental research and public health · 2020Article
- Phthalates and asthma in children and adults: US NHANES 2007-2012.Environmental science and pollution research international · 2019Article
- Pollution and respiratory disease: can diet or supplements help? A review.Respiratory research · 2018Review
- Exploitation of Trametes versicolor for bioremediation of endocrine disrupting chemicals in bioreactors.PloS one · 2017Article
- Environmental immune disruptors, inflammation and cancer risk.Carcinogenesis · 2015Review
- Analysis of protein-protein interactions in MCF-7 and MDA-MB-231 cell lines using phthalic acid chemical probes.International journal of molecular sciences · 2014Article
- Occupational asthma in a cable manufacturing company.Iranian Red Crescent medical journal · 2014Article
- Phthalate exposure and health-related outcomes in specific types of work environment.International journal of environmental research and public health · 2014Article
- Fungal laccases degradation of endocrine disrupting compounds.BioMed research international · 2014Article
- Phthalic acid chemical probes synthesized for protein-protein interaction analysis.International journal of molecular sciences · 2013Article
- Pulmonary phthalate exposure and asthma - is PPAR a plausible mechanistic link?EXCLI journal · 2013Article
- International Conference on Food and Drug Safety Assessment. Editorial.The Kaohsiung journal of medical sciences · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a chronic inflammatory disorder of the airway, characterized by airway hyperresponsiveness. It is a disabling disease with an increasing prevalence, resulting in heavy social and economic burdens worldwide. Humans are extensively exposed to phthalates, and many epidemiological studies have shown a relationship between phthalate exposure and asthma in recent decades. Earlier experimental studies focused on inflammatory cells, demonstrating the adjuvant effects, immunomodulatory effects, or immunosuppressive effects related to phthalate exposure. Recent studies have shown that phthalates may have a direct effect on airway epithelial cells and contribute to airway remodeling, which is the cardinal pathologic characteristic of chronic asthma, with a high correlation with disease severity. Through these efforts, phthalates have been recognized as important environmental factors in the pathogenesis of asthma, but further studies are still required to elucidate the detailed mechanism. This review discusses the current status of human exposure to phthalates in Taiwan and summarizes the epidemiological and experimental evidence related to the roles of phthalate exposure in the development of asthma and associated diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.