Evidence map›Paper›PMID 22869847›Full record

ArticleThe Journal of clinical endocrinology and metabolism2012

Mechanism of action of DPP-4 inhibitors--new insights.

Adrian Vella

Abstract readEditorialComment
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Dual PTP1B/DPP4 Inhibitory Potential ofComputational and structural biotechnology journal · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Black Goji Berry (Antioxidants (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Adrian Vella

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
The regulation of fasting glucose metabolism in people with and without prediabetesR01DK078646 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2007 to 2026
$8.7M
The Effect of Bariatric Surgery on Carbohydrate MetabolismR01DK082396 · NIDDK · MAYO CLINIC ROCHESTER · PI VELLA, ADRIAN · 2010 to 2014
$1.6M
NCATS NIH HHS UL1 TR000135NIDDK NIH HHS R01 DK078646NIDDK NIH HHS R01 DK082396NIDDK NIH HHS R01-DK78646NIDDK NIH HHS R01-DK82396PHS HHS UL1TR00135
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2FemaleHumansHypoglycemic AgentsMalePyrazinesSitagliptin PhosphateTriazolesHypoglycemic AgentsPyrazinesSitagliptin PhosphateTriazoles

Identifiers

PMID22869847
PMCPMC3410278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.