ArticleThe American journal of tropical medicine and hygiene2012
Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier.
Article in The American journal of tropical medicine and hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 59 citations in OpenAlex.
- Clinical Profile, Epidemiology, and Outcomes of Granulomatous Amebic Encephalitis: A Systematic Review.Open forum infectious diseases · 2026Review
- Identification of Potent and Selective Inhibitors ofJournal of medicinal chemistry · 2024Article
- DisseminatedFrontiers in medicine · 2024Article
- Effect of embelin on inhibition of cell growth and induction of apoptosis in Acanthamoeba castellanii.Archives of microbiology · 2023Article
- Opportunistic free-living amoebal pathogens.Pathogens and global health · 2022Article
- Review
- Immunopathogenicity ofInternational journal of molecular sciences · 2021Review
- A Surviving Case of Acanthamoeba Granulomatous Amebic Encephalitis in a Hematopoietic Stem Cell Transplant Recipient.The American journal of case reports · 2020Article
- Antiamoebic activity of synthetic tetrazoles against Acanthamoeba castellanii belonging to T4 genotype and effects of conjugation with silver nanoparticles.Parasitology research · 2020Article
- Drug Discovery againstPathogens (Basel, Switzerland) · 2020Review
- Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases.Journal of family medicine and primary care · 2020Article
- Treatment of toxoplasmosis: Current options and future perspectives.Food and waterborne parasitology · 2019Review
- Cellulose fibrils formation and organisation of cytoskeleton during encystment are essential for Acanthamoeba cyst wall architecture.Scientific reports · 2019Article
- Amebicidal effects of fenugreek (Food science & nutrition · 2019Article
- CYP51 as drug targets for fungi and protozoan parasites: past, present and future.Parasitology · 2018Review
- Acanthamoeba endophthalmitis during treatment for cutaneous disease in a renal transplant patient.Transplant infectious disease : an official journal of the Transplantation Society · 2018Article
- Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba.Scientific reports · 2017Article
- The Development of Drugs against Acanthamoeba Infections.Antimicrobial agents and chemotherapy · 2016Review
- Acanthamoeba castellanii Genotype T4 Stimulates the Production of Interleukin-10 as Well as Proinflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells, and Human Monocyte-Derived Macrophages.Infection and immunity · 2016Article
- A Review of the Current Research Trends in the Application of Medicinal Plants as a Source for Novel Therapeutic Agents AgainstIranian journal of pharmaceutical research : IJPR · 2016Article
Corrections and comments
- Erratum issuedUmar, Imram [corrected to Umar, Imran]
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 38-year-old male immunocompetent soldier developed generalized seizures. He underwent surgical debulking and a progressive demyelinating pseudotumor was identified. Serology and molecular testing confirmed a diagnosis of granulomatous amoebic encephalitis caused by Acanthamoeba sp. in this immunocompetent male. The patient was treated with oral voriconazole and miltefosine with Acanthamoeba titers returning to control levels and serial imaging demonstrating resolution of the residual lesion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.