Trial reportNutrition journal2012
The effects of four hypocaloric diets containing different levels of sucrose or high fructose corn syrup on weight loss and related parameters.
Trial report in Nutrition journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- High versus low-added sugar consumption for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2022Pooled it
- The effect of high-fructose corn syrup vs. sucrose on anthropometric and metabolic parameters: A systematic review and meta-analysis.Frontiers in nutrition · 2022Pooled it
- Diet Therapeutics Interventions for Obesity: A Systematic Review and Network Meta-Analysis.Journal of research in health sciences · 2021Pooled it
- Environmental interventions to reduce the consumption of sugar-sweetened beverages and their effects on health.The Cochrane database of systematic reviews · 2019Pooled it
- Trial
- Effect of sugars in solutions on subjective appetite and short-term food intake in 9- to 14-year-old normal weight boys.European journal of clinical nutrition · 2014Trial
- Trial
- Article
- Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding.Nutrients · 2016Review
- Added sugars and risk factors for obesity, diabetes and heart disease.International journal of obesity (2005) · 2016Review
- Sweeteners and health: findings from recent research and their impact on obesity and related metabolic conditions.International journal of obesity (2005) · 2016Review
- Health effects of fructose and fructose-containing caloric sweeteners: where do we stand 10 years after the initial whistle blowings?Current diabetes reports · 2015Review
- Fructose-containing sugars and cardiovascular disease.Advances in nutrition (Bethesda, Md.) · 2015Review
- Fructose content and composition of commercial HFCS-sweetened carbonated beverages.International journal of obesity (2005) · 2015Review
- Article
- The Role of Fructose, Sucrose and High-fructose Corn Syrup in Diabetes.European endocrinology · 2014Review
- The metabolic and endocrine response and health implications of consuming sugar-sweetened beverages: findings from recent randomized controlled trials.Advances in nutrition (Bethesda, Md.) · 2013Review
- The obesogenic effect of high fructose exposure during early development.Nature reviews. Endocrinology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe replacement of sucrose with HFCS in food products has been suggested as playing a role in the development of obesity as a public health issue. The objective of this study was to examine the effects of four equally hypocaloric diets containing different levels of sucrose or high fructose corn syrup (HFCS).
methodsThis was a randomized, prospective, double blind trial, with overweight/obese participants measured for body composition and blood chemistry before and after the completion of 12 weeks following a hypocaloric diet. The average caloric deficit achieved on the hypocaloric diets was 309 kcal.
resultsReductions were observed in all measures of adiposity including body mass, BMI,% body fat, waist circumference and fat mass for all four hypocaloric groups, as well as reductions in the exercise only group for body mass, BMI and waist circumference.
conclusionsSimilar decreases in weight and indices of adiposity are observed when overweight or obese individuals are fed hypocaloric diets containing levels of sucrose or high fructose corn syrup typically consumed by adults in the United States.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.