Trial reportNutrition journal2012
Randomized controlled trial of oatmeal consumption versus noodle consumption on blood lipids of urban Chinese adults with hypercholesterolemia.
Trial report in Nutrition journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02189200 (Effect of Nutritional Counseling Associated With the Ingestion of Oat Bran in Hypercholesterolemic Subjects in Secondary Prevention), which is not on this map. Cited by 20 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Nutritional Counseling Associated With the Ingestion of Oat Bran in Hypercholesterolemic Subjects in Secondary Prevention
Who cites it
20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Effects of whole grain intake on glycemic control: A meta-analysis of randomized controlled trials.Journal of diabetes investigation · 2022Pooled it
- Effect of oat supplementation interventions on cardiovascular disease risk markers: a systematic review and meta-analysis of randomized controlled trials.European journal of nutrition · 2022Pooled it
- Pooled it
- Food groups and intermediate disease markers: a systematic review and network meta-analysis of randomized trials.The American journal of clinical nutrition · 2018Pooled it
- Whole grain cereals for the primary or secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017Pooled it
- Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials.The American journal of clinical nutrition · 2014Pooled it
- Down-regulation of partial substitution for staple food by oat noodles on blood lipid levels: A randomized, double-blind, clinical trial.Journal of food and drug analysis · 2019Trial
- Dietary fiber intake and gallstones: The mediating role of serum lipids.The Journal of international medical research · 2026Article
- Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.Nutrients · 2022Review
- Article
- Ethnicity and Metabolic Syndrome: Implications for Assessment, Management and Prevention.Nutrients · 2019Review
- Dietary Fiber Intake and Type 2 Diabetes Mellitus: An Umbrella Review of Meta-analyses.Journal of chiropractic medicine · 2018Review
- Processing of oat: the impact on oat's cholesterol lowering effect.Food & function · 2018Review
- Effectiveness of a bioactive food compound in anthropometric measures of individuals with HIV/AIDS: A nonrandomized trial.PloS one · 2018Article
- Article
- Hypocholesterolemic and Prebiotic Effects of a Whole-Grain Oat-Based Granola Breakfast Cereal in a Cardio-Metabolic "At Risk" Population.Frontiers in microbiology · 2016Article
- Whole-grain food consumption in Singaporean children aged 6-12 years.Journal of nutritional science · 2016Article
- Oat consumption reduced intestinal fat deposition and improved health span in Caenorhabditis elegans model.Nutrition research (New York, N.Y.) · 2015Article
- Beneficial Effect of Higher Dietary Fiber Intake on Plasma HDL-C and TC/HDL-C Ratio among Chinese Rural-to-Urban Migrant Workers.International journal of environmental research and public health · 2015Article
- Effects of Carbohydrate and Dietary Fiber Intake, Glycemic Index and Glycemic Load on HDL Metabolism in Asian Populations.Journal of clinical medicine research · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular disease (CVD) is the leading cause of death in China and worldwide. Whole grain oats can reduce risk of CVD by reducing total and LDL-cholesterol, major risk factors for CVD. While this association has been established in many populations, data from Asian populations is limited. Thus, this study investigated the impact of oat consumption on cholesterol levels in Chinese adults. Male and female data from this work were previously published separately in mandarin in two Chinese journals. The combined male and female data were reanalyzed and are presented here.
methodsA randomized, controlled, parallel-arm study was conducted at Beijing Hospital, Beijing china. Subjects were adults (men and women) with mild to moderate hypercholesterolemia. The oat group (n=85) consumed 100 grams of instant oat cereal versus the control group (n=81) who consumed 100 grams of wheat flour-based noodles daily for 6 weeks. Laboratory and anthropometric measurements were conducted at baseline and at the end of the 6-week intervention.
resultsDietary fiber intake increased significantly in the oat group compared to the control group at the end of the 6-week intervention. Total-, LDL-cholesterol and waist circumference decreased significantly in the oat group compared to the control. HDL-cholesterol decreased significantly in the control group versus the oat group. There were no significant changes in blood pressure, other anthropometric or laboratory measures between the two groups at the end of the intervention.
conclusionsInstant oatmeal consumed daily for 6 weeks significantly increased fiber intake and decreased major risk factors for CVD in Chinese adults with hypercholesterolemia. Increased consumption of whole grains, including oats, should continue to be encouraged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.