ArticleGenetics2012
Independent FLC mutations as causes of flowering-time variation in Arabidopsis thaliana and Capsella rubella.
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Flowering time: From physiology, through genetics to mechanism.Plant physiology · 2024Review
- Article
- Molecular Evaluation of the Effects ofGenes · 2024Article
- Molecular mechanisms of adaptive evolution in wild animals and plants.Science China. Life sciences · 2023Review
- HEAT SHOCK TRANSCRIPTION FACTOR B2b acts as a transcriptional repressor of VIN3, a gene induced by long-term cold for flowering.Scientific reports · 2022Article
- Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages.Nature communications · 2022Article
- Genomic analysis of field pennycress (Thlaspi arvense) provides insights into mechanisms of adaptation to high elevation.BMC biology · 2021Article
- Gene regulatory networks controlled by FLOWERING LOCUS C that confer variation in seasonal flowering and life history.Journal of experimental botany · 2021Article
- Less Is More, Natural Loss-of-Function Mutation Is a Strategy for Adaptation.Plant communications · 2020Review
- The Floral RepressorInternational journal of molecular sciences · 2020Article
- Transposable elements drive rapid phenotypic variation inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Climate as a driver of adaptive variations in ecological strategies in Arabidopsis thaliana.Annals of botany · 2018Article
- Viroid-derived small RNA induces early flowering in tomato plants by RNA silencing.Molecular plant pathology · 2018Article
- Is Genetic Evolution Predictable?The Plant cell · 2018Article
- Parallel Evolution of Common Allelic Variants Confers Flowering Diversity inThe Plant cell · 2018Article
- The Functional Change and Deletion ofFrontiers in plant science · 2018Article
- Adaptation of Arabidopsis thaliana to the Yangtze River basin.Genome biology · 2017Article
- Changing Responses to Changing Seasons: Natural Variation in the Plasticity of Flowering Time.Plant physiology · 2017Review
- Domestication-driven Gossypium profilin 1 (GhPRF1) gene transduces early flowering phenotype in tobacco by spatial alteration of apical/floral-meristem related gene expression.BMC plant biology · 2016Article
- Habitat-Associated Life History and Stress-Tolerance Variation in Arabidopsis arenosa.Plant physiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Capsella rubella is an inbreeding annual forb closely related to Arabidopsis thaliana, a model species widely used for studying natural variation in adaptive traits such as flowering time. Although mutations in dozens of genes can affect flowering of A. thaliana in the laboratory, only a handful of such genes vary in natural populations. Chief among these are FRIGIDA (FRI) and FLOWERING LOCUS C (FLC). Common and rare FRI mutations along with rare FLC mutations explain a large fraction of flowering-time variation in A. thaliana. Here we document flowering time under different conditions in 20 C. rubella accessions from across the species' range. Similar to A. thaliana, vernalization, long photoperiods and elevated ambient temperature generally promote flowering. In this collection of C. rubella accessions, we did not find any obvious loss-of-function FRI alleles. Using mapping-by-sequencing with two strains that have contrasting flowering behaviors, we identified a splice-site mutation in FLC as the likely cause of early flowering in accession 1408. However, other similarly early C. rubella accessions did not share this mutation. We conclude that the genetic basis of flowering-time variation in C. rubella is complex, despite this very young species having undergone an extreme genetic bottleneck when it split from C. grandiflora a few tens of thousands of years ago.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.