Evidence map›Paper›PMID 22865617›Full record

ArticleInternational journal of methods in psychiatric research2012

Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States.

Ronald C Kessler, Maria Petukhova, Nancy A Sampson, Alan M Zaslavsky, Hans-Ullrich Wittchen

2 registry-linked trialsOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of methods in psychiatric research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1,095 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,095citing papers in PubMed, 9 pooled it
91.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03949569 nacompletednot on this mapstarted 2019, after this paper: background citation

A Pilot Study of the Effects of Interactions With Therapy Dogs on Child Stress Responsivity

TypeinterventionalSponsorUniversity of ChicagoRan2019 to 2022Enrolled188ConditionsStress Reaction, Behavior, SocialArmsTherapy Dog, Stuffed Toy Dog, 5 Minute Puppy Video
NCT05458362 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy of the Mobile App Augmentation to a Brief Anxiety Sensitivity Treatment

TypeinterventionalSponsorOhio UniversityRan2022 to 2022Enrolled73ConditionsAnxiety Sensitivity, AnxietyArmsBrief Enhanced Anxiety Sensitivity Treatment (Group BEAST), Control group Anxiety Sensitivity Treatment
3 · Its place in the literature

Who cites it

1,095 citing papers in PubMed, 9 syntheses or guidelines pooled it, 2,921 citations in OpenAlex.

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  10. An examination of core beliefs in generalized anxiety disorder.The British journal of clinical psychology · 2026
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  13. Compassion-focused therapy enhances outcomes of PTSD pharmacotherapy: A randomized controlled trial.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2026
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1,035 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA. ncs@hcp.med.harvard.edu
Maria Petukhova
Nancy A Sampson
Alan M Zaslavsky
Hans-Ullrich Wittchen
Harvard University · USTU Dresden · DE

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Psychometric Analyses of the CIDI-AR01MH066627 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ZASLAVSKY, ALAN M · 2002 to 2007
$2.3M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
Prevalence of and Risk and Protective Factors for Suicidal BehaviorsR01MH077883 · NIMH · HARVARD UNIVERSITY · PI NOCK, MATTHEW K · 2007 to 2009
$1.4M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
World Mental Health Consortium Annual Meetings 2008-2012U13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2008 to 2012
$647k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481FIC NIH HHS R03-TW006481NIDA NIH HHS K05 DA015799NIDA NIH HHS R01 DA016558NIDA NIH HHS R01-DA016558NIMH NIH HHS R01 MH066627NIMH NIH HHS R01 MH069864NIMH NIH HHS R01-MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R01-MH070884NIMH NIH HHS R01 MH077883NIMH NIH HHS R01-MH077883NIMH NIH HHS R01-MH66627NIMH NIH HHS R13 MH066849NIMH NIH HHS R13-MH066849NIMH NIH HHS U01 MH060220NIMH NIH HHS U01MH060220-09S1NIMH NIH HHS U01-MH60220NIMH NIH HHS U13 MH066849
6 · The paper itself

Abstract

Estimates of 12-month and lifetime prevalence and of lifetime morbid risk (LMR) of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) anxiety and mood disorders are presented based on US epidemiological surveys among people aged 13+. The presentation is designed for use in the upcoming DSM-5 manual to provide more coherent estimates than would otherwise be available. Prevalence estimates are presented for the age groups proposed by DSM-5 workgroups as the most useful to consider for policy planning purposes. The LMR/12-month prevalence estimates ranked by frequency are as follows: major depressive episode: 29.9%/8.6%; specific phobia: 18.4/12.1%; social phobia: 13.0/7.4%; post-traumatic stress disorder: 10.1/3.7%; generalized anxiety disorder: 9.0/2.0%; separation anxiety disorder: 8.7/1.2%; panic disorder: 6.8%/2.4%; bipolar disorder: 4.1/1.8%; agoraphobia: 3.7/1.7%; obsessive-compulsive disorder: 2.7/1.2. Four broad patterns of results are most noteworthy: first, that the most common (lifetime prevalence/morbid risk) lifetime anxiety-mood disorders in the United States are major depression (16.6/29.9%), specific phobia (15.6/18.4%), and social phobia (10.7/13.0%) and the least common are agoraphobia (2.5/3.7%) and obsessive-compulsive disorder (2.3/2.7%); second, that the anxiety-mood disorders with the earlier median ages-of-onset are phobias and separation anxiety disorder (ages 15-17) and those with the latest are panic disorder, major depression, and generalized anxiety disorder (ages 23-30); third, that LMR is considerably higher than lifetime prevalence for most anxiety-mood disorders, although the magnitude of this difference is much higher for disorders with later than earlier ages-of-onset; and fourth, that the ratio of 12-month to lifetime prevalence, roughly characterizing persistence, varies meaningfully in ways consistent with independent evidence about differential persistence of these disorders.

Indexed as

AdolescentAdultAnxiety DisordersDiagnostic and Statistical Manual of Mental DisordersFemaleHealth SurveysHumansMaleMiddle AgedMood DisordersPrevalencePsychiatric Status Rating ScalesRiskSurveys and QuestionnairesTime FactorsUnited States

Identifiers

PMID22865617
PMCPMC4005415
OpenAlexW1897149844

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.