ArticleDocumenta ophthalmologica. Advances in ophthalmology2012
Association between multifocal electroretinograms, optical coherence tomography and central visual sensitivity in advanced retinitis pigmentosa.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Post hoc analysis of a randomized placebo-controlled trial suggests potential visual benefits of branched-chain amino acids in retinitis pigmentosa.Scientific reports · 2025Trial
- Early detection and staging of retinitis pigmentosa using multifocal electroretinogram parameters and machine learning algorithms.Physical and engineering sciences in medicine · 2025Article
- Progression of retinitis pigmentosa on static perimetry, optical coherence tomography, and fundus autofluorescence.Scientific reports · 2023Article
- Article
- Assessing Photoreceptor Status in Retinal Dystrophies: From High-Resolution Imaging to Functional Vision.American journal of ophthalmology · 2021Article
- Detection Sensitivity of Retinitis Pigmentosa Progression Using Static Perimetry and Optical Coherence Tomography.Translational vision science & technology · 2021Article
- Early detection of cone photoreceptor cell loss in retinitis pigmentosa using adaptive optics scanning laser ophthalmoscopy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Preserved functional and structural integrity of the papillomacular area correlates with better visual acuity in retinitis pigmentosa.Eye (London, England) · 2016Article
- The Effects of Alcohol on Visual Evoked Potential and Multifocal Electroretinography.Journal of Korean medical science · 2016Article
- Assessing Photoreceptor Structure in Retinitis Pigmentosa and Usher Syndrome.Investigative ophthalmology & visual science · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the association between automated perimetry, multifocal electroretinogram (mfERG) and optical coherence tomography (OCT) measurements in patients with advanced retinitis pigmentosa (RP).
methodsTwenty-five patients with advanced RP were included. Central visual field sensitivity (VFS) was evaluated using an average of visual sensitivity value at central four test points during central 30-2 static automated perimetry. OCT imaging was conducted, and the inner and outer segment (IS/OS) line was classified into three groups: Group 1, absence; Group 2, partially intact; and Group 3, intact. Central retinal thickness (CRT) that is the retinal thickness of central 3.0 mm was also evaluated. Average amplitude and implicit time of N1 and P1 in ring 1 and 2 were measured on mfERG. Comparisons of VFS, mfERG and OCT among the three subgroups were performed following IS/OS integrity. Relationship among VFS, mfERG and CRT was evaluated by regression analysis.
resultsGroup 3 patients with an intact IS/OS line showed a better VFS, and amplitude of mfERG response than those of Group 1 and 2. VFS and amplitudes of mfERG were correlated significantly with CRT in linear regression analysis.
conclusionsDisrupted IS/OS integrity was associated with visual dysfunction which was shown by decreased amplitude of mfERG response and reduced central VFS. CRT was significantly correlated with amplitude of mfERG response and central VFS. An eye with the more reduced CRT was associated with the worse amplitude of mfERG response and central VFS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.