Evidence map›Paper›PMID 22865028›Full record

ReviewCurrent oncology reports2012

Transformation in follicular lymphoma: biology, prognosis, and therapeutic options.

Eric Wong, Michael Dickinson

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Non-Hodgkin Lymphoma Metabolism.Advances in experimental medicine and biology · 2021
    Article
  6. Article
  7. Article
  8. Progress against follicular lymphoma.Current opinion in hematology · 2013
    Review
  9. Article
  10. Non-Hodgkin Lymphoma Metabolism.Advances in experimental medicine and biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Eric WongDivision of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia. eric.wong@petermac.org
Michael Dickinson
Peter MacCallum Cancer Centre · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transformation of follicular lymphoma to an aggressive lymphoma is a well-recognised complication that occurs at a rate of approximately 3 % a year for the first 10 years of observation. Transformation is accompanied by increased risk of refractoriness and a poor expectation of survival. Genetic and epigenetic triggers for transformation have been described. Prior to routine use of rituximab, transformed lymphoma was managed in a fashion similar to that for de novo diffuse large B-cell lymphoma, with generally poor results. Rituximab appears to have improved outcomes. Some centres, including our own, use high-dose chemotherapy with stem cell transplantation as consolidation for those with responsive disease. Here, we focus on transformed follicular lymphoma, and provide an overview of the current literature and our approach to management.

Indexed as

Cell Transformation, NeoplasticAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorHumansLymphoma, FollicularLymphoma, Large B-Cell, DiffusePositron-Emission TomographyPrognosisRisk FactorsStem Cell TransplantationTransplantation, AutologousTumor MicroenvironmentBiomarkers, Tumor

Identifiers

PMID22865028
OpenAlexW2004137930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.