Evidence map›Paper›PMID 22864805›Full record

ReviewCurrent gastroenterology reports2012

The chronic gastrointestinal consequences associated with campylobacter.

Mark S Riddle, Ramiro L Gutierrez, Elena F Verdu, Chad K Porter

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02280044 (Double Blind, Placebo-Controlled Trial Assessing the Efficacy of Rifaximin in Preventing Campylobacteriosis in Subjects Challenged With Campylobacter Jejuni), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02280044 phase2 / phase3completednot on this mapstarted 2014, after this paper: background citation

Double Blind, Placebo-Controlled Trial Assessing the Efficacy of Rifaximin in Preventing Campylobacteriosis in Subjects Challenged With Campylobacter Jejuni

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2014 to 2016Enrolled30ConditionsDysentery, Diarrhea, Enteric CampylobacteriosisArmsRifaximin intervention, Placebo intervention
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Lack of homologous protection against Campylobacter jejuni CG8421 in a human challenge model.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Diversity ofmSphere · 2024
    Article
  8. Whole-genome sequences ofMicrobiology resource announcements · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Update on Campylobacter vaccine development.Human vaccines & immunotherapeutics · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Mark S RiddleEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910, USA. mark.riddle@med.navy.mil
Ramiro L Gutierrez
Elena F Verdu
Chad K Porter
Naval Medical Research Command · USMcMaster University · CAWalter Reed National Military Medical Center · US

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Campylobacteriosis is a leading cause of acute infectious diarrhea in the developing world, where it causes considerable mortality, and in developed countries, where it accounts for significant healthcare and other costs. Evidence has emerged from basic science, clinical, and epidemiological domains that suggests that Campylobacter infection is not limited to acute illness but is also involved in the development of well-described extraintestinal sequelae, such as the Guillain-Barré syndrome and reactive arthritis, and may also contribute to the pathogenesis of chronic gastrointestinal conditions. This review will focus on the role of Campylobacter infection as a risk factor for the development of chronic gastrointestinal sequelae, such as functional gastrointestinal disorders, with which irritable bowel syndrome has been most frequently associated, inflammatory bowel disease, and celiac disease.

Indexed as

CampylobacterCampylobacter InfectionsCeliac DiseaseCost of IllnessGastrointestinal DiseasesHumansIncidenceInflammatory Bowel Diseases

Identifiers

PMID22864805
OpenAlexW2076621036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.