Evidence map›Paper›PMID 22864399›Full record

Trial reportJournal of addiction medicine2012

Persistence on a stress-challenge task before initiating buprenorphine treatment was associated with successful transition from opioid use to early abstinence.

David R Strong, Richard A Brown, Meredith Sims, Debra S Herman, Bradley J Anderson, Michael D Stein

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of addiction medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Article
  3. Climate Change and Substance-Use Behaviors: A Risk-Pathways Framework.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023
    Article
  4. Prelimbic Cortex Activity during a Distress Tolerance Task Predicts Cocaine-Seeking Behavior in Male, But Not Female Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Distress tolerance among emergency department patients in acute pain: Associations with substance use treatment.Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Distress tolerance trajectories following substance use treatment.Journal of consulting and clinical psychology · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David R StrongDepartment of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Dr. #0813, La Jolla, CA 92093, USA. dstrong@ucsd.edu
Richard A Brown
Meredith Sims
Debra S Herman
Bradley J Anderson
Michael D Stein

Funding

Antidepressants During Office-based BuprenorphineR01DA022207 · NIDA · RHODE ISLAND HOSPITAL · PI STEIN, MICHAEL D · 2006 to 2008
$1.0M
MIDCAREER INVESTIGATOR AWARD IN SUBSTANCE ABUSE RESEARCHK24DA000512 · NIDA · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI STEIN, MICHAEL D · 2001 to 2010
$982k
DISCOVERY OF NOVEL MOLECULAR TARGETS FOR ENDOGENOUS AND SYNTHETIC CANNABINOIDSZ01DA000512 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI SHIPPENBERG, TONI · 2007 to 2008
$189k
Intramural NIH HHS Z01 DA000512NIDA NIH HHS DA022207NIDA NIH HHS K24 DA000512NIDA NIH HHS R01 DA022207
6 · The paper itself

Abstract

objectivesLapse to opiate use after initiation of buprenorphine treatment is common and is a strong predictor of poor treatment retention and increased risk of long-term opiate use. Drug cues and situations or events associated with distress are known to provoke craving and increase risk for lapse. This study evaluated the predictive validity of a behavioral index of persistence during a stress challenge among opiate users identified as affectively vulnerable to lapse risk due to elevated depressive symptoms.

methodsPatients from an ongoing clinical trial (n = 48) completed a stress-challenge task before receiving their first dose of buprenorphine.

resultsAfter controlling for levels of craving on their induction day, persistence on the stress-challenge task before initiating buprenorphine treatment was associated with successful transition to early abstinence, and lower rates of opiate use during the initial 3 months of buprenorphine treatment across antidepressant and placebo groups.

conclusionsResults from this preliminary study suggest the promise of laboratory-based behavioral paradigms in facilitating an understanding of important mechanisms of early lapse. Identifying individual behavioral responses to drug and stress cues before attempts at abstinence may facilitate delivery of adjunctive behavioral treatments to prevent early lapse.

Indexed as

MotivationSubstance Abuse DetectionAdultAntidepressive Agents, Second-GenerationBuprenorphineCitalopramComorbidityDepressive DisorderDouble-Blind MethodDrug Therapy, CombinationFemaleHumansMaleMedication AdherenceMiddle AgedNarcoticsAntidepressive Agents, Second-GenerationBuprenorphineCitalopramNarcotics

Identifiers

PMID22864399
PMCPMC3980199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.