Replication origins run (ultra) deep.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Nonreplicative functions of the origin recognition complex.Nucleus (Austin, Tex.) · 2018
   Review
2. A journey through the microscopic ages of DNA replication.Protoplasma · 2017
   Review
3. Replicating Large Genomes: Divide and Conquer.Molecular cell · 2016
   Review
4. The Histone Variant H3.3 Is Enriched at Drosophila Amplicon Origins but Does Not Mark Them for Activation.G3 (Bethesda, Md.) · 2016
   Article
5. G-quadruplexes and their regulatory roles in biology.Nucleic acids research · 2015
   Review
6. DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in Drosophila.Nucleic acids research · 2015
   Article
7. High-resolution profiling of Drosophila replication start sites reveals a DNA shape and chromatin signature of metazoan origins.Cell reports · 2015
   Article
8. Peaks cloaked in the mist: the landscape of mammalian replication origins.The Journal of cell biology · 2015
   Review
9. Best practices for mapping replication origins in eukaryotic chromosomes.Current protocols in cell biology · 2014
   Review
10. Origin replication complex binding, nucleosome depletion patterns, and a primary sequence motif can predict origins of replication in a genome with epigenetic centromeres.mBio · 2014
    Article
11. The spatiotemporal program of DNA replication is associated with specific combinations of chromatin marks in human cells.PLoS genetics · 2014
    Article
12. Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts.Nucleic acids research · 2013
    Article
13. High-resolution analysis of DNA synthesis start sites and nucleosome architecture at efficient mammalian replication origins.The EMBO journal · 2013
    Article
14. Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle.PLoS genetics · 2013
    Article
15. Developmental control of replication timing defines a new breed of chromosomal domains with a novel mechanism of chromatin unfolding.Nucleus (Austin, Tex.)
    Article

Corrections and comments

• Comment on
  Unraveling cell type-specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs.2012

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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