ReviewBest practice & research. Clinical endocrinology & metabolism2012
Subclinical hyperfunctioning pituitary adenomas: the silent tumors.
Review in Best practice & research. Clinical endocrinology & metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03714763 (The Predictive Value of Positron Emission Tomography-Magnetic Resonance), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Predictive Value of Positron Emission Tomography-Magnetic Resonance (PET-MR) Mediated Dopamine D2 Receptors Imaging in the Drug Therapy of Nonfunctioning Pituitary Adenoma
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Predictors of silent corticotroph adenoma recurrence; a large retrospective single center study and systematic literature review.Pituitary · 2018Pooled it
- Somatic USP8 alteration affects the immune landscape of corticotroph pituitary adenomas- a pilot study.Hormones (Athens, Greece) · 2024Article
- Article
- Aggressive nonfunctioning pituitary neuroendocrine tumors.Brain tumor pathology · 2022Review
- Distribution of E- and N-cadherin in subgroups of non-functioning pituitary neuroendocrine tumours.Endocrine · 2022Article
- Silent Corticotroph and Somatotroph Double Pituitary Adenoma: A Case Report and Review of Literature.Journal of neurological surgery reports · 2022Article
- The silent variants of pituitary tumors: demographic, radiological and molecular characteristics.Journal of endocrinological investigation · 2021Observational
- Plurihormonal pituitary macroadenoma: a case report.Journal of medical case reports · 2021Article
- Is there any gender difference in epidemiology, clinical presentation and co-morbidities of non-functioning pituitary adenomas? A prospective survey of a National Referral Center and review of the literature.Journal of endocrinological investigation · 2021Article
- Article
- Clinicopathological analysis of 250 cases of pituitary adenoma under the new WHO classification.Oncology letters · 2020Article
- Clinical and Pathological Aspects of Silent Pituitary Adenomas.The Journal of clinical endocrinology and metabolism · 2019Review
- Aggressive somatotrophinomas lacking clinical symptoms: neurosurgical management.Neurosurgical review · 2018Article
- Silent somatotroph pituitary adenomas: an update.Pituitary · 2018Review
- Histopathological classification of non-functioning pituitary neuroendocrine tumors.Pituitary · 2018Review
- Management of non-functioning pituitary adenomas: surgery.Pituitary · 2018Review
- Is it time to consider the expression of specific-pituitary hormone genes when typifying pituitary tumours?PloS one · 2018Article
- Article
- Article
- Early postoperative growth in non-functioning pituitary adenomas; A tool to tailor safe follow-up.Endocrine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Pituitary adenomas are classified by function as defined by clinical symptoms and signs of hormone hypersecretion with subsequent confirmation on immunohistochemical staining. However, positive immunostaining for pituitary cell types has been shown for clinically nonfunctioning adenomas, and this entity is classified as silent functioning adenoma. Most common in these subtypes include silent gonadotroph adenomas, silent corticotroph adenomas and silent somatotroph adenomas. Less commonly, silent prolactinomas and thyrotrophinomas are encountered. Appropriate classification of these adenomas may affect follow-up care after surgical resection. Some silent adenomas such as silent corticotroph adenomas follow a more aggressive course, necessitating closer surveillance. Furthermore, knowledge of the immunostaining characteristics of silent adenomas may determine postoperative medical therapy. This article reviews the incidence, clinical behavior, and pathologic features of clinically silent pituitary adenomas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.