ArticleBMC genomics2012
Comparative analysis of the Oenococcus oeni pan genome reveals genetic diversity in industrially-relevant pathways.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 92 citations in OpenAlex.
- Metabolic behavior for a mutantFrontiers in microbiology · 2023Article
- Genomic Analysis of an Excellent Wine-Making StrainPolish journal of microbiology · 2022Article
- Exploring the diversity of bacteriophage specific to Oenococcus oeni and Lactobacillus spp and their role in wine production.Applied microbiology and biotechnology · 2021Review
- Analysis of Transcriptomic Response to SOMicrobiology spectrum · 2021Article
- Distribution of Prophages in theMicroorganisms · 2021Article
- Article
- Characterization of the First Virulent Phage InfectingFrontiers in microbiology · 2020Article
- Lysogeny in the Lactic Acid Bacterium Oenococcus oeni Is Responsible for Modified Colony Morphology on Red Grape Juice Agar.Applied and environmental microbiology · 2019Article
- Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains.BMC genomics · 2019Article
- Distribution of Oenococcus oeni populations in natural habitats.Applied microbiology and biotechnology · 2019Review
- New Insights Into Cinnamoyl Esterase Activity ofFrontiers in microbiology · 2019Article
- Bacteriophages as an Up-and-Coming Alternative to the Use of Sulfur Dioxide in Winemaking.Frontiers in microbiology · 2019Article
- Complete Genome Sequence of Lytic Oenococcus oeni Bacteriophage OE33PA.Microbiology resource announcements · 2018Article
- Biogeography of Oenococcus oeni Reveals Distinctive but Nonspecific Populations in Wine-Producing Regions.Applied and environmental microbiology · 2017Article
- Genome-Scale Reconstruction of the Metabolic Network inFrontiers in microbiology · 2017Article
- Carbohydrate metabolism in Oenococcus oeni: a genomic insight.BMC genomics · 2016Article
- Stress Physiology of Lactic Acid Bacteria.Microbiology and molecular biology reviews : MMBR · 2016Review
- The Variable Regions of Lactobacillus rhamnosus Genomes Reveal the Dynamic Evolution of Metabolic and Host-Adaptation Repertoires.Genome biology and evolution · 2016Article
- Article
- Analysis of pan-genome to identify the core genes and essential genes of Brucella spp.Molecular genetics and genomics : MGG · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOenococcus oeni, a member of the lactic acid bacteria, is one of a limited number of microorganisms that not only survive, but actively proliferate in wine. It is also unusual as, unlike the majority of bacteria present in wine, it is beneficial to wine quality rather than causing spoilage. These benefits are realised primarily through catalysing malolactic fermentation, but also through imparting other positive sensory properties. However, many of these industrially-important secondary attributes have been shown to be strain-dependent and their genetic basis it yet to be determined.
resultsIn order to investigate the scale and scope of genetic variation in O. oeni, we have performed whole-genome sequencing on eleven strains of this bacterium, bringing the total number of strains for which genome sequences are available to fourteen. While any single strain of O. oeni was shown to contain around 1800 protein-coding genes, in-depth comparative annotation based on genomic synteny and protein orthology identified over 2800 orthologous open reading frames that comprise the pan genome of this species, and less than 1200 genes that make up the conserved genomic core present in all of the strains. The expansion of the pan genome relative to the coding potential of individual strains was shown to be due to the varied presence and location of multiple distinct bacteriophage sequences and also in various metabolic functions with potential impacts on the industrial performance of this species, including cell wall exopolysaccharide biosynthesis, sugar transport and utilisation and amino acid biosynthesis.
conclusionsBy providing a large cohort of sequenced strains, this study provides a broad insight into the genetic variation present within O. oeni. This data is vital to understanding and harnessing the phenotypic variation present in this economically-important species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.