Evidence map›Paper›PMID 22860899›Full record

ArticleJournal of the American Geriatrics Society2012

Evaluation of two fatigability severity measures in elderly adults.

John F Schnelle, Maciej S Buchowski, Talat A Ikizler, Daniel W Durkin, Linda Beuscher, Sandra F Simmons

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03800342 nacompletednot on this mapstarted 2019, after this paper: background citation

Recovery, Fatigability, and Proteomic Response to Aerobic Exercise Training in Healthy Individuals

TypeinterventionalSponsorGeorge Mason UniversityRan2019 to 2019Enrolled21ConditionsAdult, FatigueArmsAerobic Exercise Training
NCT03864393 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of a 12-week Multimodal Exercise Intervention on Walking Economy, Fatigability, and Propulsion in Individuals With Parkinson's Disease

TypeinterventionalSponsorGeorge Mason UniversityRan2019 to 2020Enrolled17ConditionsParkinson DiseaseArmsMultimodal overground locomotor training
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Higher Striatal Dopamine is Related With Lower Physical Performance Fatigability in Community-Dwelling Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  7. Article
  8. Article
  9. Validation of the Pittsburgh Performance Fatigability Index in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Changes in Objectively Measured Physical Activity Are Associated With Perceived Physical and Mental Fatigability in Older Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  15. Article
  16. Evaluating Test-Retest Reliability of Fatigability in Chronic Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021
    Article
  17. Article
  18. Comment on "Fatigability: A Prognostic Indicator of Phenotypic Aging".The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  19. Measures of excessPilot and feasibility studies · 2021
    Article
  20. Aerobic capacity and fatigability are associated with activity levels in women with hip osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

John F SchnelleDivision of General Internal Medicine and Public Health, Center for Quality Aging, Vanderbilt University, Nashville, Tennessee; Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, Nashville, Tennessee.
Maciej S Buchowski
Talat A Ikizler
Daniel W Durkin
Linda Beuscher
Sandra F Simmons
Vanderbilt Health · USVanderbilt University · USGeriatric Research Education and Clinical Center · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0M
A novel approach to predict energy of physical activityR01DK069465 · NIDDK · VANDERBILT UNIVERSITY · PI BUCHOWSKI, MACIEJ S · 2004 to 2008
$1.6M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) TL1TL1RR024978 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$1.3M
NCRR NIH HHS KL2 RR024977NCRR NIH HHS TL1 RR024978NCRR NIH HHS UL1 RR024975NCRR NIH HHS UL1RR024975NIDDK NIH HHS DK2059NIDDK NIH HHS R01 DK069465
6 · The paper itself

Abstract

objectivesTo document the stability, concurrent validity, and clinical correlates of two fatigability severity measures as recommended by the American Geriatrics Society.

designDescriptive, cross-sectional.

settingTwo independent living and one community senior centers.

participantsForty-three participants, with an average age 85 ± 6. MEASUREMENTS: Perceived fatigability severity was quantified by directly asking participants to report change in energy after a standardized 10-minute walk at a self-selected pace. Performance fatigability severity was defined as a ratio of change in walking speed to total distance walked. The walk test was repeated within 2 weeks to assess stability. Total daily physical activity (PA) was measured over 7 consecutive days using a waist-worn accelerometer. Frailty was measured using the Vulnerable Elders Survey interview scale, and gait speed was measured using a standardized 25-feet walk test.

resultsThe perceived and performance fatigability severity measures were significantly correlated (correlation coefficient (r) = 0.94, P < .001) and stable over two assessments (r = 0.82 and 0.85, P < .001). Both fatigability severity measures were significantly correlated with PA level (r = -0.42 and r = -0.44, respectively, P = .02), frailty (r = 0.47 and 0.53, respectively, P = .001) and gait speed (r = -0.45, P = .003 and r = -0.54, P = .001, respectively).

conclusionThe methodology described in this study permits the calculation of two highly correlated fatigability severity scores, which summarize the relationship between a person's change in self-reported tiredness or change in physical performance and concurrently measured PA. The fatigability severity scores are reproducible and correlated with clinical measures predictive of decline. The methods used to quantify fatigability severity can be implemented during a brief assessment (<15 minutes) and should be useful in the design and evaluation of interventions to increase PA in older adults at risk of functional decline.

Indexed as

AgedAged, 80 and overCross-Sectional StudiesFatigueFemaleGeriatric AssessmentHumansMaleSeverity of Illness Index

Identifiers

PMID22860899
PMCPMC3419324
OpenAlexW2076734429

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.