ArticlePloS one2012
Light-induced oxidative stress, N-formylkynurenine, and oxygenic photosynthesis.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Trp521 oxidation affects FtsH2 stability and its role in PSII repair.The New phytologist · 2026Article
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- Melatonin Type 2 Receptor Activation Regulates Blue Light Exposure-Induced Mouse Corneal Epithelial Damage by Modulating Impaired Autophagy and Apoptosis.International journal of molecular sciences · 2022Article
- Metabolomic Insights of the Effects of Bacterial Algicide IRI-160AA on DinoflagellateMetabolites · 2022Article
- Singlet-Oxygen-Induced Phospholipase AChemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Measuring ROS and redox markers in plant cells.RSC chemical biology · 2021Review
- Phloroglucinol Strengthens the Antioxidant Barrier and Reduces Oxidative/Nitrosative Stress in Nonalcoholic Fatty Liver Disease (NAFLD).Oxidative medicine and cellular longevity · 2021Article
- Impaired PSII proteostasis triggers a UPR-like response in the var2 mutant of Arabidopsis.Journal of experimental botany · 2019Article
- Oxidative post-translational modification of EXECUTER1 is required for singlet oxygen sensing in plastids.Nature communications · 2019Article
- ROS-Driven Oxidative Modification: Its Impact on Chloroplasts-Nucleus Communication.Frontiers in plant science · 2019Review
- Chloroplast protein homeostasis is coupled with retrograde signaling.Plant signaling & behavior · 2019Article
- Singlet Oxygen Metabolism: From Genesis to Signaling.Frontiers in plant science · 2019Review
- Reactive oxygen species leave a damage trail that reveals water channels in Photosystem II.Science advances · 2017Article
- An unusual role for the phytyl chains in the photoprotection of the chlorophylls bound to Water-Soluble Chlorophyll-binding Proteins.Scientific reports · 2017Article
- FtsH2-Dependent Proteolysis of EXECUTER1 Is Essential in Mediating Singlet Oxygen-Triggered Retrograde Signaling inFrontiers in plant science · 2017Article
- Alternatives to the 'water oxidation pathway' of biological ozone formation.Journal of chemical biology · 2016Article
- The Use of Advanced Mass Spectrometry to Dissect the Life-Cycle of Photosystem II.Frontiers in plant science · 2016Review
- Tripping up Trp: Modification of protein tryptophan residues by reactive oxygen species, modes of detection, and biological consequences.Free radical biology & medicine · 2015Review
- Article
- Reactive oxygen and oxidative stress: N-formyl kynurenine in photosystem II and non-photosynthetic proteins.Photosynthesis research · 2012Review
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light stress in plants results in damage to the water oxidizing reaction center, photosystem II (PSII). Redox signaling, through oxidative modification of amino acid side chains, has been proposed to participate in this process, but the oxidative signals have not yet been identified. Previously, we described an oxidative modification, N-formylkynurenine (NFK), of W365 in the CP43 subunit. The yield of this modification increases under light stress conditions, in parallel with the decrease in oxygen evolving activity. In this work, we show that this modification, NFK365-CP43, is present in thylakoid membranes and may be formed by reactive oxygen species produced at the Mn(4)CaO(5) cluster in the oxygen-evolving complex. NFK accumulation correlates with the extent of photoinhibition in PSII and thylakoid membranes. A modest increase in ionic strength inhibits NFK365-CP43 formation, and leads to accumulation of a new, light-induced NFK modification (NFK317) in the D1 polypeptide. Western analysis shows that D1 degradation and oligomerization occur under both sets of conditions. The NFK modifications in CP43 and D1 are found 17 and 14 Angstrom from the Mn(4)CaO(5) cluster, respectively. Based on these results, we propose that NFK is an oxidative modification that signals for damage and repair in PSII. The data suggest a two pathway model for light stress responses. These pathways involve differential, specific, oxidative modification of the CP43 or D1 polypeptides.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.