ArticlePLoS biology2012
Chromatin proteins: key responders to stress.
Article in PLoS biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
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- Comparative Physiological, Biochemical, and Leaf Proteome Responses of Contrasting Wheat Varieties to Drought Stress.Plants (Basel, Switzerland) · 2024Article
- Control of Gene Expression via the Yeast CWI Pathway.International journal of molecular sciences · 2022Review
- Hypothesis and Theory: Roles of Arginine Methylation in C9orf72-Mediated ALS and FTD.Frontiers in cellular neuroscience · 2021Article
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- Heritable stress response dynamics revealed by single-cell genealogy.Science advances · 2018Article
- Utilization of Different Omic Approaches to Unravel Stress Response Mechanisms in the ParasiteFrontiers in cellular and infection microbiology · 2018Review
- Regulation of gene expression is associated with tolerance of the Arctic copepodEcology and evolution · 2017Article
- H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis.Nature communications · 2017Article
- Identification of Crowding Stress Tolerance Co-Expression Networks Involved in Sweet Corn Yield.PloS one · 2016Article
- A Specialized Histone H1 Variant Is Required for Adaptive Responses to Complex Abiotic Stress and Related DNA Methylation in Arabidopsis.Plant physiology · 2015Article
- Functional role of histone variant Htz1 in the stress response to oleate in Saccharomyces cerevisiae.Bioscience reports · 2015Article
- Tau promotes neurodegeneration through global chromatin relaxation.Nature neuroscience · 2014Article
- Plant tolerance to high temperature in a changing environment: scientific fundamentals and production of heat stress-tolerant crops.Frontiers in plant science · 2013Article
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2 authors at 1 institution in 1 country.
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Abstract
Environments can be ever-changing and stresses are commonplace. In order for organisms to survive, they need to be able to respond to change and adapt to new conditions. Fortunately, many organisms have systems in place that enable dynamic adaptation to immediate stresses and changes within the environment. Much of this cellular response is coordinated by modulating the structure and accessibility of the genome. In eukaryotic cells, the genome is packaged and rolled up by histone proteins to create a series of DNA/histone core structures known as nucleosomes; these are further condensed into chromatin. The degree and nature of the condensation can in turn determine which genes are transcribed. Histones can be modified chemically by a large number of proteins that are thereby responsible for dynamic changes in gene expression. In this Primer we discuss findings from a study published in this issue of PLoS Biology by Weiner et al. that highlight how chromatin structure and chromatin binding proteins alter transcription in response to environmental changes and stresses. Their study reveals the importance of chromatin in mediating the speed and amplitude of stress responses in cells and suggests that chromatin is a critically important component of the cellular response to stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.