Evidence map›Paper›PMID 22859855›Full record

ReviewJournal of the American Society of Nephrology : JASN2012

Treatment of idiopathic membranous nephropathy.

Meryl Waldman, Howard A Austin

Abstract readReview
In one paragraph

Review in Journal of the American Society of Nephrology : JASN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Mechanism of action ofRenal failure · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meryl WaldmanKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. waldmanm@niddk.nih.gov
Howard A Austin

Funding

Multidisciplinary Collaborative Research in NIDDK Program Area DiseasesZIDDK070013 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOH, CHRISTOPHER · 2009 to 2025
$19.9M
Sirolimus Therapy in Idiopathic and Lupus Membranous NephropathyZIADK061500 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BALOW, JAMES · 2009 to 2014
$1.0M
Intramural NIH HHS
6 · The paper itself

Abstract

Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Rituximab, mycophenolate mofetil, and adrenocorticotropic hormone, with an emphasis on results of the most recent clinical trials.

Indexed as

Adrenocorticotropic HormoneAlkylating AgentsAntibodies, Monoclonal, Murine-DerivedCalcineurin InhibitorsClinical Trials as TopicGlomerulonephritis, MembranousHumansImmunosuppressive AgentsMycophenolic AcidReceptors, Phospholipase A2RituximabAdrenocorticotropic HormoneAlkylating AgentsAntibodies, Monoclonal, Murine-DerivedCalcineurin InhibitorsImmunosuppressive AgentsMycophenolic AcidReceptors, Phospholipase A2Rituximab

Identifiers

PMID22859855
PMCPMC3458460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.