ArticleClinical journal of the American Society of Nephrology : CJASN2012
Association of interleg BP difference with overall and cardiovascular mortality in hemodialysis.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 41 citations in OpenAlex.
- The Association of Four-Limb Blood Pressure with History of Stroke in Chinese Adults: A Cross-Sectional Study.PloS one · 2015Trial
- Longitudinal Associations between Changes in Inter-Ankle SBP Difference and Cardiovascular Events and Mortality in the ARIC Study.American journal of hypertension · 2025Article
- Inter-leg systolic blood pressure difference has been associated with all-cause and cardiovascular mortality: analysis of NHANES 1999-2004.BMC public health · 2024Article
- Association between interleg systolic blood pressure difference and apparent peripheral neuropathy in US adults with diabetes: a cross-sectional study.Journal of health, population, and nutrition · 2023Article
- Non-invasive hemodynamic diagnosis based on non-linear pulse wave theory applied to four limbs.Frontiers in bioengineering and biotechnology · 2023Article
- Arterial stiffness and contralateral differences in blood pressure: The Atherosclerosis Risk in Communities (ARIC) study.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Article
- Upstroke Time as a Novel Predictor of Mortality in Patients with Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2020Article
- Predicting Stroke Outcomes Using Ankle-Brachial Index and Inter-Ankle Blood Pressure Difference.Journal of clinical medicine · 2020Article
- Association of 4-limb systolic blood pressure heterogeneity with peripheral artery disease and left ventricular mass index.Medicine · 2020Observational
- Usefulness of four-limb blood pressure measurement in prediction of overall and cardiovascular mortality in acute myocardial infarction.International journal of medical sciences · 2020Article
- [Research on the cardiovascular function evaluation system based on noninvasive detection indices].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019Article
- Significance of the combination of inter-limb blood pressure differences in the elderly: The Northern Shanghai Study.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Four-Limb Blood Pressure Measurement with an Oscillometric Device: a Tool for Diagnosing Peripheral Vascular Disease.Current hypertension reports · 2019Review
- Brachial-ankle pulse wave velocity, cardio-ankle vascular index, and prognosis.Vascular health and risk management · 2018Review
- Interankle Systolic Blood Pressure Difference Is a Marker of Prevalent Stroke in Chinese Adults: A Cross-Sectional Study.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Association of simultaneously measured four-limb blood pressures with cardiovascular function: a cross-sectional study.Biomedical engineering online · 2016Article
- Observational
- Valuation of Normal Range of Ankle Systolic Blood Pressure in Subjects with Normal Arm Systolic Blood Pressure.PloS one · 2015Article
- Sites of peripheral artery occlusive disease as a predictor for all-cause and cardiovascular mortality in chronic hemodialysis.PloS one · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesAn interarm BP difference has been associated with atherosclerosis and adverse cardiovascular outcomes. This study investigated whether an interleg BP difference was associated with peripheral vascular disease and overall and cardiovascular mortality in hemodialysis patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This study enrolled 210 hemodialysis patients from December 2006 to January 2007. Bilateral leg BPs were measured simultaneously by an ankle-brachial index (ABI)-form device before hemodialysis.
resultsThe mean follow-up period was 4.4±1.5 years. ABI <0.9 and high brachial-ankle pulse wave velocity were independently associated with an interleg difference in systolic BP of ≥15 mmHg or diastolic BP of ≥10 mmHg. Furthermore, this difference was an independent predictor for overall mortality (hazard ratio [HR], 3.36; 95% confidence interval [CI], 1.68-6.72; P<0.01) and cardiovascular mortality (HR, 4.84; 95% CI, 1.84-12.71; P<0.01) after adjustment for demographic, clinical, and biochemical parameters. After further adjustment for ABI <0.9 and brachial-ankle pulse wave velocity, the relation remained significant to overall mortality (HR, 2.91; 95% CI, 1.28-6.64; P=0.01) and cardiovascular mortality (HR, 3.15; 95% CI, 1.05-9.44; P=0.04).
conclusionsA difference in systolic BP of ≥15 mmHg or diastolic BP of ≥10 mmHg between legs was associated with peripheral vascular disease and increased risk for overall and cardiovascular mortality in hemodialysis patients. Detection of an interleg BP difference may identify hemodialysis patients at increased risk of peripheral vascular disease and overall and cardiovascular mortality.
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