Evidence map›Paper›PMID 22855829›Full record

ReviewGenes & development2012

Condensins: universal organizers of chromosomes with diverse functions.

Tatsuya Hirano

Abstract readReview
In one paragraph

Review in Genes & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 250 papers.

0numbers the graph read from it
0cells of the map it votes in
250citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

250 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. ChIA-PET Analysis for Investigating SMC-Mediated 3D Genomic Contacts.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  14. Purification and In Vitro Analysis of Escherichia coli RecN.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  15. An integrated roadmap of European sea bass (Frontiers in cell and developmental biology · 2026
    Article
  16. Review
  17. Organization principles of dynamic three-dimensional genome architecture associated with centromere clustering states.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. RecessiveDiagnostics (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Article

190 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tatsuya HiranoChromosome Dynamics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama, Japan. hiranot@riken.jp

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Condensins are multisubunit protein complexes that play a fundamental role in the structural and functional organization of chromosomes in the three domains of life. Most eukaryotic species have two different types of condensin complexes, known as condensins I and II, that fulfill nonoverlapping functions and are subjected to differential regulation during mitosis and meiosis. Recent studies revealed that the two complexes contribute to a wide variety of interphase chromosome functions, such as gene regulation, recombination, and repair. Also emerging are their cell type- and tissue-specific functions and relevance to human disease. Biochemical and structural analyses of eukaryotic and bacterial condensins steadily uncover the mechanisms of action of this class of highly sophisticated molecular machines. Future studies on condensins will not only enhance our understanding of chromosome architecture and dynamics, but also help address a previously underappreciated yet profound set of questions in chromosome biology.

Indexed as

Adenosine TriphosphatasesAnimalsChromosomesChromosome SegregationDNA-Binding ProteinsEukaryotaHumansMeiosisMitosisMultiprotein ComplexesAdenosine Triphosphatasescondensin complexesDNA-Binding ProteinsMultiprotein Complexes

Identifiers

PMID22855829
PMCPMC3418584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.