ArticleWorld journal of hepatology2012
A half century (1961-2011) of applying microsurgery to experimental liver research.
Article in World journal of hepatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Immunological Rejection in a Heterotopic Rat Liver Transplant Model.Transplantation proceedings · 2025Article
- Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review.Iranian journal of basic medical sciences · 2024Review
- The 3Rs in Experimental Liver Disease.Animals : an open access journal from MDPI · 2023Review
- The progress to establish optimal animal models for the study of acute-on-chronic liver failure.Frontiers in medicine · 2023Review
- Article
- Surgical Models to Explore Acellular Liver Scaffold Transplantation: Step-by-Step.Organogenesis · 2020Article
- Hepatic Encephalopathy-Associated Cerebral Vasculopathy in Acute-on-Chronic Liver Failure: Alterations on Endothelial Factor Release and Influence on Cerebrovascular Function.Frontiers in physiology · 2020Article
- Pine ( Pinus densiflora ) needle extract could promote the expression of PCNA and Ki-67 after partial hepatectomy in rat.Acta cirurgica brasileira · 2019Article
- Associating liver partition and portal vein ligation for staged hepatectomy: establishment of an animal model with insufficient liver remnant.Laboratory investigation; a journal of technical methods and pathology · 2019Article
- Validation of control genes and a standardised protocol for quantifying gene expression in the livers of C57BL/6 and ApoE-/- mice.Scientific reports · 2018Article
- A Rat Model of Orthotopic Liver Transplantation Using a Novel Magnetic Anastomosis Technique for Suprahepatic Vena Cava Reconstruction.Journal of visualized experiments : JoVE · 2018Article
- Decompensated liver cirrhosis and neural regulation of mesenteric vascular tone in rats: role of sympathetic, nitrergic and sensory innervations.Scientific reports · 2016Article
- Bile duct ligation in mice: induction of inflammatory liver injury and fibrosis by obstructive cholestasis.Journal of visualized experiments : JoVE · 2015Article
- Article
- Experimental liver fibrosis research: update on animal models, legal issues and translational aspects.Fibrogenesis & tissue repair · 2013Article
- Liver scaffolds obtained by decellularization: A transplant perspective in liver bioengineering.Journal of tissue engineeringArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of microsurgery has been dependent on experimental animals. Microsurgery could be a very valuable technique to improve experimental models of liver diseases. Microdissection and microsutures are the two main microsurgical techniques that can be considered for classifying the experimental models developed for liver research in the rat. Partial portal vein ligation, extrahepatic cholestasis and hepatectomies are all models based on microdissection. On the other hand, in portacaval shunts, orthotopic liver transplantation and partial heterotopic liver transplantation, the microsuture techniques stand out. By reducing surgical complications, these microsurgical techniques allow for improving the resulting experimental models. If good experimental models for liver research are successfully developed, the results obtained from their study might be particularly useful in patients with liver disease. Therefore experimental liver microsurgery could be an invaluable way to translate laboratory data on liver research into new clinical diagnostic and therapeutic strategies.
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