Evidence map›Paper›PMID 22855512›Full record

ArticleJournal of clinical microbiology2012

Genetic characterization of Trichomonas vaginalis isolates by use of multilocus sequence typing.

Denise C Cornelius, D Ashley Robinson, Christina A Muzny, Leandro A Mena, David M Aanensen, William B Lushbaugh, John C Meade

Registry-linked trialOpen access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01546714 (Sexually Transmitted Infections Among African American Women Who Have Sex With Women), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01546714 completednot on this map

Sexually Transmitted Infections Among African American Women Who Have Sex With Women

TypeobservationalSponsorUniversity of Alabama at BirminghamRan2011 to 2013Enrolled165ConditionsSexually Transmitted Infections
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
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  6. Prevalence and Genotype ofJournal of tropical medicine · 2023
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  9. A review onSouthern African journal of infectious diseases · 2021
    Review
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  15. Article
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  18. Review
  19. Article
  20. Considerable Genetic Diversity ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Denise C CorneliusDepartment of Microbiology, University of Mississippi Medical Center, Jackson, MS, USA.
D Ashley Robinson
Christina A Muzny
Leandro A Mena
David M Aanensen
William B Lushbaugh
John C Meade
University of Mississippi Medical Center · USImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we introduce a multilocus sequence typing (MLST) scheme, comprised of seven single-copy housekeeping genes, to genetically characterize Trichomonas vaginalis. Sixty-eight historical and recent isolates of T. vaginalis were sampled from the American Type Culture Collection and female patients at area health care facilities, respectively, to assess the usefulness of this typing method. Forty-three polymorphic nucleotide sites, 51 different alleles, and 60 sequence types were distinguished among the 68 isolates, revealing a diverse T. vaginalis population. Moreover, this discriminatory MLST scheme retains the ability to identify epidemiologically linked isolates such as those collected from sexual partners. Population genetic and phylogenetic analyses determined that T. vaginalis population structure is strongly influenced by recombination and is composed of two separate populations that may be nonclonal. MLST is useful for investigating the epidemiology, genetic diversity, and population structure of T. vaginalis.

Indexed as

DNA, ProtozoanFemaleHumansMolecular EpidemiologyMolecular Sequence DataMultilocus Sequence TypingParasitologyPolymorphism, GeneticSequence Analysis, DNATrichomonas InfectionsTrichomonas vaginalisDNA, Protozoan

Identifiers

PMID22855512
PMCPMC3457461
OpenAlexW2118872233

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.