Evidence map›Paper›PMID 22855485›Full record

ArticleJournal of virology2012

Acute diarrhea in West African children: diverse enteric viruses and a novel parvovirus genus.

Tung G Phan, Nguyen P Vo, Isidore J O Bonkoungou, Amit Kapoor, Nicolas Barro, Miguel O'Ryan, Beatrix Kapusinszky, Chunling Wang, Eric Delwart

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 2 syntheses or guidelines pooled it, 152 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  11. Presence of herpesviruses, parvoviruses, and polyomaviruses in sinonasal lymphoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Old and Novel Enteric Parvoviruses of Dogs.Pathogens (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Article
  19. Gut virome in early life: origins and implications.Current opinion in virology · 2022
    Review
  20. First report of canine bufavirus in India.Archives of virology · 2022
    Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Tung G PhanBlood Systems Research Institute, San Francisco, California, USA.
Nguyen P Vo
Isidore J O Bonkoungou
Amit Kapoor
Nicolas Barro
Miguel O'Ryan
Beatrix Kapusinszky
Chunling Wang
Eric Delwart
Blood Systems Research Institute · USUniversité Joseph Ki-Zerbo · BFHo Chi Minh City Medicine and Pharmacy University · VNStanford Medicine · USUniversity of California, San Francisco · USUniversity of Chile · CL

Funding

Metagenomic detection of emerging viruses in the blood supplyR01HL105770 · NHLBI · VITALANT · PI DELWART, ERIC L · 2011 to 2015
$2.4M
Metagenomic analysis of the human viromeR01HL083254 · NHLBI · VITALANT · PI DELWART, ERIC L · 2007 to 2010
$1.6M
NHLBI NIH HHS R01 HL083254NHLBI NIH HHS R01HL083254NHLBI NIH HHS R01 HL105770
6 · The paper itself

Abstract

Parvoviruses cause a variety of mild to severe symptoms or asymptomatic infections in humans and animals. During a viral metagenomic analysis of feces from children with acute diarrhea in Burkina Faso, we identified in decreasing prevalence nucleic acids from anelloviruses, dependoviruses, sapoviruses, enteroviruses, bocaviruses, noroviruses, adenoviruses, parechoviruses, rotaviruses, cosavirus, astroviruses, and hepatitis B virus. Sequences from a highly divergent parvovirus, provisionally called bufavirus, were also detected whose NS1 and VP1 proteins showed <39% and <31% identities to those of previously known parvoviruses. Four percent of the fecal samples were PCR positive for this new parvovirus, including a related bufavirus species showing only 72% identity in VP1. The high degree of genetic divergence of these related genomes from those of other parvoviruses indicates the presence of a proposed new Parvoviridae genus containing at least two species. Studies of the tropism and pathogenicity of these novel parvoviruses will be facilitated by the availability of their genome sequences.

Indexed as

Base SequenceBurkina FasoCapsid ProteinsChild, PreschoolDiarrheaFecesGenetic VariationGenome, ViralHumansParvoviridae InfectionsParvovirusSequence Analysis, DNASequence Analysis, RNAViral Nonstructural ProteinsCapsid Proteinscapsid protein VP1, parvovirus B19NS1 protein, parvovirusViral Nonstructural Proteins

Identifiers

PMID22855485
PMCPMC3457132
OpenAlexW2150417877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.