Evidence map›Paper›PMID 22855422›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Dual-function CXCR4 antagonist polyplexes to deliver gene therapy and inhibit cancer cell invasion.

Jing Li, Yu Zhu, Stuart T Hazeldine, Chunying Li, David Oupický

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
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  5. Article
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  10. Preferential siRNA delivery to injured kidneys for combination treatment of acute kidney injury.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
  11. Review
  12. Article
  13. Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing LiDepartment of Pharmaceutical Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48202, USA.
Yu Zhu
Stuart T Hazeldine
Chunying Li
David Oupický

Funding

Drug-based polycations for combination drug-gene deliveryR21EB014570 · NIBIB · WAYNE STATE UNIVERSITY · PI OUPICKY, DAVID · 2012 to 2013
$410k
NIBIB NIH HHS EB014570NIBIB NIH HHS R21 EB014570
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BenzylaminesCell Line, TumorCell MovementCell SurvivalChemokine CXCL12CyclamsGene Transfer TechniquesHep G2 CellsHeterocyclic CompoundsHumansReceptors, CXCR4RNA InterferenceRNA, Small InterferingBenzylaminesChemokine CXCL12CyclamsHeterocyclic CompoundsplerixaforReceptors, CXCR4RNA, Small Interfering

Identifiers

PMID22855422
PMCPMC3517087

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.