Evidence map›Paper›PMID 22855315›Full record

ReviewSchmerz (Berlin, Germany)2012

[Pediatric caudal anesthesia: importance and aspects of safety concerns].

J Mauch, M Weiss

Registry-linked trialAbstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Schmerz (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02769390 (Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias Surgery), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02769390 phase2completednot on this mapstarted 2015, after this paper: background citation

Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias Surgery

TypeinterventionalSponsorFederal University of Minas GeraisRan2015 to 2015Enrolled80ConditionsPostoperative PainArmsClonidine 1 mcg/Kg, Clonidine 2 mcg/ Kg, Clonidine 3 mcg/ Kg
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J MauchAnästhesieabteilung, Universitäts-Kinderkliniken Zürich, Steinwiesstr. 75, 8032, Zürich, Schweiz. jacqueline.mauch@kispi.uzh.ch
M Weiss

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caudal block is a safe procedure commonly used for pediatric perioperative analgesia. Complications are extremely rare but nevertheless local and systemic contraindications must be excluded. Optimal safety and quality result when strict attention is paid to technical details. A local anesthetic (LA) containing epinephrine allows early detection of inadvertent intravascular LA administration; therefore an epinephrine/LA mixture is recommended at least for the test dose. In terms of safety the choice of LA itself is probably of secondary importance. Clonidine as an adjuvant has an excellent risk/benefit profile with minimal side effects. Inadvertent systemic LA intoxication is a rare but potentially fatal complication of regional anesthesia and measures for prevention and early detection are essential. Should circulatory arrest occur, immediate resuscitation following standard guidelines is to be initiated including the use of epinephrine as the first line drug. Intravenous administration of lipid solutions may be beneficial as a secondary adjunct to stabilize hemodynamics but is not an alternative to epinephrine.

Indexed as

Adjuvants, AnesthesiaAnesthesia, CaudalAnesthetics, LocalBlood PressureChildClonidineElectrocardiographyEpinephrineFat Emulsions, IntravenousGuideline AdherenceHumansPatient SafetyPostoperative PainResuscitationShockAdjuvants, AnesthesiaAnesthetics, LocalClonidineEpinephrineFat Emulsions, Intravenous

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.