Evidence map›Paper›PMID 22855214›Full record

SynthesisWorld journal of surgery2012

Single-incision laparoscopic cholecystectomy versus conventional laparoscopic cholecystectomy: meta-analysis and systematic review of randomized controlled trials.

Muhammad S Sajid, Nikhil Ladwa, Lorain Kalra, Kristian K Hutson, Krishna K Singh, Mazin Sayegh

Registry-linked trialAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02149797 (Prospective Randomized Comparative Study of New Single-incision Laparoscopic Cholecystectomy Technique, "Pick'n Roll", Versus Conventional Four-port Laparoscopic Cholecystectomy), which is not on this map. Cited by 35 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02149797 nacompletednot on this mapstarted 2014, after this paper: background citation

Prospective Randomized Comparative Study of New Single-incision Laparoscopic Cholecystectomy Technique, "Pick'n Roll", Versus Conventional Four-port Laparoscopic Cholecystectomy

TypeinterventionalSponsorSamsun Education and Research HospitalRan2014 to 2014Enrolled60ConditionsCholelithiasisArmsFour port laparoscopic cholecystectomy, SILC-Pick'n roll-Beginning (group I), SILC-Pick'n roll-Experienced (group II)
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  8. [Operation time for suprapubic transumbilical cholecystectomy: Results of a prospective randomized trial].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2015
    Trial
  9. Trial
  10. Article
  11. ArtiSentialAnnals of hepato-biliary-pancreatic surgery · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015
    Article
  19. Single-incision laparoscopic cholecystectomy versus mini-laparoscopic cholecystectomy: A randomized clinical trial study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammad S SajidDepartment of Upper Gastrointestinal and Hepatobiliary Surgery, Worthing Hospital, Worthing, Washington Suite, North Wing, West Sussex, BN11 2DH, UK. surgeon1wrh@hotmail.com
Nikhil Ladwa
Lorain Kalra
Kristian K Hutson
Krishna K Singh
Mazin Sayegh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to analyze systematically the randomized, controlled trials that compared single-incision laparoscopic cholecystectomy (SILC) and conventional laparoscopic cholecystectomy (CLC).

methodsThe meta-analysis was conducted according to the Quality of Reporting of Meta-analysis (QUORUM) standards. The included studies were analyzed systematically using the statistical software package RevMan. The summated outcomes were expressed as the risk ratios (RR) for dichotomous variables and standardized mean differences (SMD) for continuous variables.

resultsEleven randomized trials encompassing 858 patients were retrieved from the electronic databases. In the random effects model, postoperative pain, postoperative complications, length of hospital stay, cosmesis score, conversion rate, and time to return to normal activities were statistically comparable between the two cholecystectomy techniques. SILC was associated with a longer operating time [SMD 0.71; 95 % confidence interval (CI) 0.38, 1.05; z = 4.18; p < 0.0001) and an increased requirement for additional port insertion (RR 6.54; 95 % CI 2.19, 19.57; z = 3.36; p < 0008). However, there was significant heterogeneity among the trials.

conclusionsSILC does not offer any advantage over CLC for treating benign gallbladder disorders. CLC may be used assiduously for this purpose.

Indexed as

Cholecystectomy, LaparoscopicHumansRandomized Controlled Trials as Topic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.