Evidence map›Paper›PMID 22854915›Full record

ReviewLab on a chip2012

Optofluidic detection for cellular phenotyping.

Yi-Chung Tung, Nien-Tsu Huang, Bo-Ram Oh, Bishnubrata Patra, Chi-Chun Pan, Teng Qiu, Paul K Chu, Wenjun Zhang, Katsuo Kurabayashi

Abstract readReview
In one paragraph

Review in Lab on a chip, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. 3D printed microfluidic devices with electrodes for electrochemical analysis.Analytical methods : advancing methods and applications · 2024
    Review
  3. Review
  4. Review
  5. Droplet Microfluidics for Microbial Biotechnology.Advances in biochemical engineering/biotechnology · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Yi-Chung TungResearch Center for Applied Sciences, Academia Sinica, 128 Sec. 2, Academia Rd. Nankang, Taipei, 11529, Taiwan.
Nien-Tsu Huang
Bo-Ram Oh
Bishnubrata Patra
Chi-Chun Pan
Teng Qiu
Paul K Chu
Wenjun Zhang
Katsuo Kurabayashi
University of Michigan–Ann Arbor · USAcademia Sinica · TWCity University of Hong Kong · HKNational Yang Ming Chiao Tung University · TWShanghai Fudan Microelectronics (China) · CNSoutheast University · CN

Funding

Targeted Multi-Spectral Dual Axes Confocal Imaging of In Vivo Molecular ExpressioR01CA142750 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KURABAYASHI, KATSUO, LUKER, GARY D · 2010 to 2014
$2.4M
NCI NIH HHS R01 CA142750NCI NIH HHS R01-CA-142750-01
6 · The paper itself

Abstract

Quantitative analysis of the output of processes and molecular interactions within a single cell is highly critical to the advancement of accurate disease screening and personalized medicine. Optical detection is one of the most broadly adapted measurement methods in biological and clinical assays and serves cellular phenotyping. Recently, microfluidics has obtained increasing attention due to several advantages, such as small sample and reagent volumes, very high throughput, and accurate flow control in the spatial and temporal domains. Optofluidics, which is the attempt to integrate optics with microfluidics, shows great promise to enable on-chip phenotypic measurements with high precision, sensitivity, specificity, and simplicity. This paper reviews the most recent developments of optofluidic technologies for cellular phenotyping optical detection.

Indexed as

Cell NucleusCytoplasmHumansInterferometryMicrofluidicsOptics and PhotonicsPhenotypePrecision MedicineSpectrometry, FluorescenceSpectrum Analysis, RamanSurface Plasmon Resonance

Identifiers

PMID22854915
PMCPMC3815588
OpenAlexW1968525684

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.