ArticleNature cell biology2012
FOXOphagy path to inducing stress resistance and cell survival.
Article in Nature cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 50 citations in OpenAlex.
- FOXO: a key target in regulating aging and age-related diseases.Biogerontology · 2026Review
- Amino acids metabolism: a potential target for cancer treatment.Molecular cancer · 2025Review
- Role of O-linked N-acetylglucosamine protein modification in oxidative stress-induced autophagy: a novel target for bone remodeling.Cell communication and signaling : CCS · 2024Review
- High water temperature raised the requirements of methionine for spotted seabass (Lateolabrax maculatus).Fish physiology and biochemistry · 2024Article
- Transcription factor FoxO1 regulates myoepithelial cell diversity and growth.Scientific reports · 2024Article
- Effects of Dietary Supplementation with Glutamine on the Immunity and Intestinal Barrier Gene Expression in Broiler Chickens Infected withAnimals : an open access journal from MDPI · 2022Article
- Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.International journal of molecular sciences · 2021Review
- Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma.Cells · 2021Article
- C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene.Scientific reports · 2019Article
- Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy.Oxidative medicine and cellular longevity · 2018Review
- Simulation of Cellular Energy Restriction in Quiescence (ERiQ)-A Theoretical Model for Aging.Biology · 2017Article
- Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis.The Journal of clinical investigation · 2017Article
- MTOR controls genesis and autophagy of GABAergic interneurons during brain development.Autophagy · 2017Article
- C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy.Molecular cancer · 2017Article
- PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.CNS neuroscience & therapeutics · 2017Article
- The effect of Bacopa monnieri on gene expression levels in SH-SY5Y human neuroblastoma cells.PloS one · 2017Article
- MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy.Frontiers in molecular neuroscience · 2017Article
- Therapeutic targeting of autophagy in cardiovascular disease.Journal of molecular and cellular cardiology · 2016Review
- Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6.SpringerPlus · 2016Review
- Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy.Nature communications · 2015Article
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
Abstract
Nutrient deprivation and other stress stimuli elicit metabolic changes (such as the induction of autophagy and activation of FOXO transcription factors) that help an organism adapt to stressful conditions. A link between these stress response pathways is revealed by the finding that FOXO3 upregulates the expression of glutamine synthetase to promote glutamine accumulation, inhibit mTOR signalling and promote autophagy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.